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Attention and memory in illicit amphetamine users
Institution:1. Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Neuroscience Paris Seine – Institut de Biologie Paris Seine (NPS – IBPS), 75005 Paris, France;2. Laboratory of Cerebrovascular Research, Montreal Neurological Institute, McGill University, Montréal, QC, Canada H3A 2B4;1. Department of Psychology, PMB 407817, Vanderbilt University, 2301 Vanderbilt Place, Nashville, TN 37240-7817, United States;2. Department of Psychiatry, Vanderbilt University School of Medicine, 1601 23rd Ave South, Suite 3057, Nashville, TN 37212, United States;3. Department of Radiology, UAB School of Medicine, United States;1. Singapore Eye Research Institute, Singapore National Eye Centre, Singapore;2. Duke-NUS Medical School, Singapore;3. Centre for Vision Research, Westmead Institute for Medical Research, University of Sydney, Sydney, Australia;4. Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Abstract:The purpose of this study was to assess cognitive functioning in a group of illicit amphetamine users. A neuropsychological test battery (Wechsler Memory Scale-Revised (WMS-R) and the digit symbol, block design and vocabulary subtests of the Wechsler Adult Intelligence Scale-Revised (WAIS-R) and the National Adult Reading Test (NART)) was administered to 78 amphetamine users (mean age=22.5 years; 46 males, 33 females). Severity of amphetamine dependence was found to be associated with poorer performance on both memory and attention/concentration indices of the WMS-R. The relative contribution of amphetamine dependence, concurrent drug use and other drug related factors to neuropsychological functioning are discussed.
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