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| 藜芦提取物的体外DPPH自由基清除作用和对PC9肺癌细胞增殖的影响 | |
| 引用本文： | 金善花,姜成哲,崔正云,尹希俊,安仁波.藜芦提取物的体外DPPH自由基清除作用和对PC9肺癌细胞增殖的影响[J].中国中医药现代远程教育,2010,8(20):180-181. |
| 作者姓名： | 金善花 姜成哲 崔正云 尹希俊 安仁波 |
| 作者单位： | 1. 吉林省延边中医医院,133000 2. 吉林省延边大学农学院,133400 3. 吉林省延边大学药学院,133000 |
| 摘 要： | 目的探讨藜芦（Veratrum nigrum）提取物对DPPH自由基清除作用和对人体肺癌细胞系PC9细胞增殖的影响，比较藜芦的水提物与醇提物的作用差异。方法DPPH自由基清除法和CCK-8细胞毒性检测法。结果藜芦水提物和醇提物在10mg／ml时体外DPPH清除率分别为52．3％和42，8％。在体外培养的条件下能明显抑制PC9细胞的增殖，并且呈浓度依赖性，而水提物只在高浓度时有抑制作用。结论藜芦提取物具有DPPH自由基清除作用，并且对PC9细胞的体外增殖有明显的抑制作用。 |
| 关 键 词： | 藜芦提取物 DPPH PC9细胞 细胞毒性 |
Investigate the Effects of Two Kinds of Extracts from LiLu(Veratrum nigrum)on DPPH Radical Clearing and on the Proliferation of Human Lung Cancer PC9 Cells |
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| Jin Shanhua,Jiang Chengzhe,Cui Zhengyun,Yin Xijun,An Renbo.Investigate the Effects of Two Kinds of Extracts from LiLu(Veratrum nigrum)on DPPH Radical Clearing and on the Proliferation of Human Lung Cancer PC9 Cells[J].Chinese Medicine Modern Distance Education of China,2010,8(20):180-181. | |
| Authors: | Jin Shanhua Jiang Chengzhe Cui Zhengyun Yin Xijun An Renbo |
| Institution: | 1. Yanbian Traditianal Hospital Jinlin Yanji, 1330001 2.Agricultural College of Tanbian University, Jilin Langjing 133400; 3. Pharmaceutical College of Yanbian University, Jilin Longjing 133000) |
| Abstract: | Purpose To investigate the effects of two kinds of extracts from LiLu （Veratrum nigrum） on DPPH radical clearing and on the proliferation of human lung cancer PC9 cells. Methods PC9 cells were treated with various concentrations of methanol or water extract from LLLu respectively. Cell proliferation of each sample was measured 72 hours after treatment by CCK-8 ldt. Results Those extracts significantly inhibited the proliferation of PC9 cells on dose-dependent manner. （DPPH？） Conclusion Extracts of Lilu exert inhibitory effects on proliferation of PC9 lung cancer cens in vitro. |
| Keywords: | DPPH |
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