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齐拉西酮与利培酮治疗精神分裂症对照研究
引用本文:张述杰,王美娟,胡君,赵路平,郭影.齐拉西酮与利培酮治疗精神分裂症对照研究[J].中国民康医学,2008,20(17):2002-2003.
作者姓名:张述杰  王美娟  胡君  赵路平  郭影
作者单位:沈阳精神卫生中心,辽宁沈阳,110168
摘    要:目的:探讨齐拉西酮与利培酮治疗精神分裂症的疗效和安全性。方法:将60例精神分裂症患者随机分为齐拉西酮组和利培酮组,每组30例。疗程8周,采用阳性与阴性症状量表(PANSS)和治疗中出现的症状量表(TESS)评定疗效和不良反应。结果:齐拉西酮组有效率83.3%,显效率70.0%,利培酮组有效率86.7%,显效率73.3%。结论:齐拉西酮治疗精神分裂症疗效较好与利培酮相当,不良反应少。

关 键 词:齐拉西酮  利培酮  精神分裂症

Comparative analysis between ziprasidone and risperidone in teratment of schizophrenia
ZHAMG Shu-jie,WANG Mei-juan,HU jun,et al.Comparative analysis between ziprasidone and risperidone in teratment of schizophrenia[J].medical journal of chinese peoples health,2008,20(17):2002-2003.
Authors:ZHAMG Shu-jie  WANG Mei-juan  HU jun  
Institution:Shenyang Mental Health Center Shebyabg 110168 Liaoning
Abstract:Objective:To explore the efficacy and safety of ziprasidone in treatment of schizophrenia.Methods:60 patients with schizophreia were randomly assigned two groups ziprasidone group(n=30) and respenridone group(n=30) for 8 week.Positive and negative syndrome scale(PANSS) and treatment side effect scale(TESS)were used to evaluate the efficacy and side effects respectively.Results: The response rate and marked response rate was 83.3% and70.0% in ziprasidone treatment patients,and which was 86.7% and 73.3% in risperidone randomly patients.Conclusions: Ziprasidone has better treatment efficacy and less adverse effects in schizophrenia.
Keywords:Ziprasidone  Resperidone  Schizophrenia
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