抗磷脂综合征患者妊娠结局分析

目的探讨妊娠并抗磷脂综合征患者的妊娠结局及相关护理。方法，选择抗心磷脂抗体（ACA）阳性孕妇40例作为观察组和40例ACA阴性的孕妇为对照组，比较两组患者的妊娠结局情况。结果观察组发生流产6例（15．0％），死胎2例（5．0％），妊娠丢失8例（20．0％）；对照组发生流产2例（5．0％），无死胎，妊娠丢失2例（5．0％）；观察组妊娠丢率失明显高于对照组（χ^2=9．54，P〈0．05）；采用相应治疗护理后（孕中期）ACA—Igg阳性率达40．0％低于治疗前的52．5％（χ^2=3．85，P〈0．05）；产后1月ACA—IgM阳性率37．5％低于孕中期40．0％（χ^2=3．81，P〈0．05）。结论ACA阳性与妊娠丢失有密切的关系，采取相应的治疗护理干预可提高疗效，减少妊娠并发症。

Nursing intervention of pregnant women with antiphospholipid syndrome

Objective To investigate the nursing intervention of pregnant women with antiphespholipid syndrome(APS). Methods In experimental group 40 cases with APS positive and control group 40 cases with APS ACA-negative for comparison. Results The abortion occurred in 6 cases(15. 0%) ,2 cases of stillbirth(5.0%) ,loss of pregnancy(abortion+stillbirth) 8 cases (20. 0%) in experimental group. The abortion occurred in 2 cases (5.0%), no stillbirth in control group. The loss of pregnancy in experimental group were significantly higher than the control group (X2=9. 54, P＜0. 005 ). The rate of positive in ACA-IgG (40. 0%) after treatment lower than before treatment (52. 5 %) (X2 = 3.85, P＜0. 05). The rate of positive in ACA IgM (37. 5%) after treatment lower than before treatment(40. 0)% (X2=3.81 ,P＜0. 05 ). Conclusion The APS positive rate and the loss of pregnancy were closely related. The overall nursing intervention conld improve efficacy and reduce the complications.