| 凝血酶激活的纤溶抑制物与缺血性脑血管病 |
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| 引用本文： | 宋兴刚,许延路.凝血酶激活的纤溶抑制物与缺血性脑血管病[J].国际脑血管病杂志,2006,14(6):459-461. |
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| 作者姓名： | 宋兴刚 许延路 |
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| 作者单位： | 250014,济南安康医院神经内科 |
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| 摘 要： | 凝血酶激活的纤溶抑制物(TAFI)是近年来发现的一种新型凝血和纤溶调控因子。活化的TAFI(TAFIa)能使纤溶酶失去与纤维蛋白的作用位点而发挥纤溶抑制作用和促进血栓形成。深入研究TAFI有可能为缺血性脑血管病的治疗提供一种新的选择。
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| 关 键 词： | 凝血酶 纤维蛋白溶解 缺血性脑血管病 血栓形成 |
| 收稿时间： | 2006-01-19 |
| 修稿时间： | 2006-03-27 |
Thrombin-Activatable Fibrinolysis Inhibitor and Ischemic Cerebrovascular Disease |
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| Xing-Gang Song,Yan-Lu Xu.Thrombin-Activatable Fibrinolysis Inhibitor and Ischemic Cerebrovascular Disease[J].International Journal of Cerebrovascular Diseases,2006,14(6):459-461. |
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| Authors: | Xing-Gang Song Yan-Lu Xu |
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| Institution: | Department of Neurology, Jinan Ankang Hospital, Jinan 250014, China |
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| Abstract: | Thrombin activatable fibrinolysis inhibitor (TAFI), a novel regulator of coagulation and fibrinolysis, was discovered recently. The activated TAFI (TAFIa) makes fibrinolysin lose its action sites with fibrin, and thus exerts its fibrinolytic inhibition and promotes thrombosis. Making a thorough study of TAFI may provide a new option for the treatment of ischemic cerebrovascular disease. |
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| Keywords: | thrombin fibrinolysis ischemic cerebrovascular disease thrombosis |
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