艾灸督脉对肾精亏虚型卒中后轻度认知障碍患者认知功能和中医症状的临床疗效研究

背景 卒中后轻度认知障碍（PSMCI）是卒中后患者常见并发症，影响患者全面康复的同时也给其家庭带来了经济和精神方面的压力。 目的 观察艾灸督脉对肾精亏虚型PSMCI患者认知功能及中医症状的临床疗效。 方法 选取2020年7月至2021年7月河南中医药大学第一附属医院康复中心收治的符合纳入标准的PSMCI患者60例为研究对象，采用随机数字表法将其分为艾灸组和对照组，每组30例。对照组患者给予常规基础治疗及常规认知功能康复训练，艾灸组患者在对照组基础上进行艾灸督脉治疗，1次/d，5次/周，持续4周。比较治疗前后两组患者简易智能精神状态量表（MMSE）、蒙特利尔认知评估量表（MoCA）、血管性痴呆中医辨证量表（SDSVD）中肾精亏虚型和脑卒中专用生活质量量表（SS-QOL）评分，并评定两组治疗的临床疗效和安全性。 结果 艾灸组患者治疗前后MMSE、MoCA、SDSVD、SS-QOL评分差值大于对照组（P<0.05）。艾灸组患者治疗后临床疗效优于对照组（P<0.05）。两组患者治疗安全性比较，差异无统计学意义（P>0.05）。 结论 艾灸督脉可以改善PSMCI患者的认知功能和中医症状，临床疗效佳，且安全性较好。

Moxibustion on Governor Vessel Acupoints Improves the Cognitive Function and TCM Symptoms in Patients with Post-stroke Mild Cognitive Impairment Due to Deficiency of Kidney Essence

Background Post-stroke mild cognitive impairment(PSMCI)is a common complication after stroke,which negatively affects patients'full recovery from stroke and imposes financial and emotional pressure on their families.Objective To observe the clinical efficacy of moxibustion on Governor vessel on the cognitive function and TCM syndromes in PSMCI due to deficiency of kidney essence.Methods Eligible patients with PSMCI(n=60)who were treated in Rehabilitation Center,the First Affiliated Hospital of Henan University of CM from July 2020 to July 2021 were selected,and evenly randomized to a control group(routine basic treatment plus routine cognitive rehabilitation training)and a moxibustion group〔routine basic treatment plus routine cognitive rehabilitation training and moxibustion on the Governor vessel acupoints(once daily,five times per week)〕,received four consecutive weeks of treatment.The Mini-Mental State Examination(MMSE),and Montreal Cognitive Assessment(MoCA)were used to assess the cognitive function.Symptoms of kidney essence deficiency was assessed by the Scale for the Differentiation of Syndromes of Vascular Dementia(SDSVD).And quality of life was measured by the Specifications for Stroke-Quality of Life(SS-QOL).The overall clinical efficacy and safety of the two treatments were evaluated.Results Pre-and post-treatment comparisons of scores of MMSE and MoCA,SDSVD,and SS-QOL revealed that moxibustion group patients group had greater improvements in cognitive function,symptoms of kidney essence deficiency,and quality of life than control group patients(P<0.05).Moreover,moxibustion group patients had better clinical outcomes(P<0.05).The safety of treatment showed no significant intergroup differences(P>0.05).Conclusion Moxibustion of the Governor vessel helps to better improve the cognitive function and TCM symptoms of PSMCI patients due to deficiency of kidney essence with good clinical efficacy and safety.