超声心动图评价糖尿病患者左心功能变化的可行性研究

目的 探讨超声心动图在评价糖尿病（DM）患者左心功能变化的临床应用价值.方法 选择2010年1月～2011年4月诸暨市人民医院（以下简称“我院”）收治的无心脏病症状DM患者43例,按病程分为A组26例（发病＞2年）,B组17例（发病≤2年）;选择同期于我院行健康体检者30例（C组）.所有研究对象均行彩色多普勒超声心动图检测,观察并比较相关指标.结果 ①A组和B组患者左室舒张末期内径（LVIDd）（57.9±4.2）、（47.5±3.7）mm]、室间隔舒张末期内径（IVSd）（32.4±3.2）、（30.2±3.1）mm]、左室后壁舒张末期厚度（LVPWd） （11.5±1.2）、（9.8±0.9）mm]及LVMI（65.7±4.6）％、（67.5±4.9）％）]明显增加,与C组比较差异有统计学意义（P＜0.05）.A组患者左房前后径（LAd）（39.2±3.2）mm]明显增高,与C组（29.2±2.4）mm]比较,差异有统计学意义（P＜0.05）.A组LAd、LVIDd、IVSd、LVPWD及LVMI较B组明显增加,两组比较差异有统计学意义（P＜0.05）.②A组和B组患者Tei指数（0.69±0.24）、（0.52±0.16）]明显增加,E/A（0.78±0.32）、（0.83±0.35）]、Ea/Aa（0.67±0.29）、（0.89±0.21）]明显降低,与C组比较差异有统计学意义（P＜0.05）.A组患者A（75.3±8.9）cm/s]和Aa（12.4±1.6） cm/s]明显增高,与C组（67.9±5.4）、（8.9±2.1）cm/s]比较,差异有统计学意义（P＜0.05）.A组A、Aa及Tei指数较B组明显增加,E/A、Ea/Aa较B组明显降低,两组比较差异有统计学意义（P＜0.05）.结论 超声心动图检查可早期发现DM患者心脏解剖结构异常表现和对左心室舒张功能进行评估.

Study on the feasibility of evaluating changes of left ventricular funetionin patients with diabetes mellitus heart disease by echocardiography

Objective To investigate the clinic value of echocardiograhy in diagnose the left ventricular function of diabetes mellitus （DM）.Methods 43 type 2 DM patients without evidences of heart diseases in People＇s Hospital of Zhuji City （＂our hospital＂ for short） from January 2010 to April 2011 were selected.43 type 2 DM patients without evidences of heart diseases were divided into group A with 26 cases （＞2 years） and group B with 17 cases （≤2 years） according to the course of the disease.30 health people in the same term were chosen as group C.All the research objects were examined by echocardiography,correlation indexes were observed and compared.Results ①LVIDd （57.9±4.2）,（47.5±3.7） mm],IVSd （32.4±3.2）,（30.2±3.1） mm],LVPWd （11.5±1.2）,（9.8±0.9） mm] and LVMI （65.7±4.6）％,（67.5±4.9）％] in group A and group B were higher than those in group C,the differences were statistically significant （P ＜ 0.05）.LAd in group A （39.2±3.2） mm]was higher than that in group C （29.2±2.4） mm],the differences were statistically significant （P ＜ 0.05）.LAd,LVIDd,IVSd,LVPWd and LVMI in group A were higher than those in group B,the differences were statistically significant （P ＜ 0.05）.②Tei index in group A and group B （0.69±0.24）,（0.52±0.16）] was higher than that in group C,the differences were statistically significant （P ＜ 0.05）.E/A （0.78±0.32）,（0.83±0.35）] and Ea/Aa （0.67±0.29）,（0.89±0.21）] was lower than that in group C,the differences were statistically significant （P ＜ 0.05）.A （75.3±8.9） cm/s],Aa （12.4±1.6） cm/s] in group A was significantly higher than that in C group （67.9±5.4）,（8.9±2.1） cm/s],the differences were statistically significant （P ＜ 0.05）.A,Aa and Tei index in group A was higher than that in group B （P ＜ 0.05） and E/A,Ea/Aa was lower than that in group B,the differences were statistically significant （P ＜ 0.05）.Conclusion Echocardiography can early detect cardiac changes and assess the left ventricular diastolic function.