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消化系疾患的血清氨基酸检测
引用本文:吴昀,奚为乎,徐晓,朱祖明. 消化系疾患的血清氨基酸检测[J]. 苏州大学学报(自然科学版), 1989, 0(3)
作者姓名:吴昀  奚为乎  徐晓  朱祖明
作者单位:苏州医学院脑神经研究室(吴昀,奚为乎),苏州医学院附属第一医院内科(徐晓),苏州医学院附属第一医院内科(朱祖明)
摘    要:本文报告50名正常人及73例消化系疾病患者血清游离氨基酸检测结果。使用氨基酸自动分析仪,对血中40余种氨基酸组分进行定性定量测定。肝硬化病人芳香氨基酸显著升高,支/芳分子比值明显低于正常值(P<0.01),甲硫氨酸、色氨酸均升高.肝脓疡.消化道肿瘤患者也有此种变化(P<0.05)。统计21种组分中,各病理组有10多种组分有非常显著差异(P<0.01)。结果提示:血液氨基酸测定可为某些消化系疾患,尤其是肝病的诊治提供较好指标。本文改进自动分析条件,节省时间。节约试剂。

关 键 词:消化系疾患  氨基酸  芳香氨基酸  支链氨基酸  支/芳分子比值

The Determinations of serum Amino Acids on Digestive System Diseases
Wu Yun et al. The Determinations of serum Amino Acids on Digestive System Diseases[J]. Suzhou University Journal of Medical Science, 1989, 0(3)
Authors:Wu Yun et al
Affiliation:Wu Yun et al
Abstract:The data of serum amino-acids on 50 cases of healthy presons and 73 cases of diges-tive system diseases determined by HITACHI High Speed Amino-Acide Analyzer were re-ported.The aromatic amino acids increased significantly in the patients with cirrhosis(P<0.01) as well as in the liver abscess and digestive cancers (P<0.01) that than in normal.There were more than 10 compositions with markedly significant difference in 21 aminoacids (P<0.01). The results suggested that the measurement of amino acids in blood maybe provided as a useful marker for some degestive diseases,especially for the liver diseases.The autoanalysis conditions were improved for saving time and reagents.
Keywords:digestive system disease  amino acid  aromatic amino acid  branched-chain amino acid  BCAA/AAA molecular ratio
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