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502例药品不良反应/事件报告综合评价
引用本文:李刚,黄文志,龙恩武,陈岷.502例药品不良反应/事件报告综合评价[J].药物流行病学杂志,2010(2):81-84.
作者姓名:李刚  黄文志  龙恩武  陈岷
作者单位:四川省人民医院药剂科;四川省药品不良反应监测中心;
摘    要:目的:提高药品不良反应(ADR)监测水平,为临床合理用药提供参考。方法:对我中心2008年1月~12月收集到的药品不良反应/事件(ADR/ADE)报告502例,从年龄和性别分布、药品分类、给药途径、严重的ADR以及不合理用药案例进行统计分析。结果:502例ADR/ADE中,大于60岁的患者占48.21%,抗感染药物占48.01%,严重ADR占5.98%,不合理用药导致药品不良事件(ADE)被认定为ADR的占10.16%。结论:加大合理用药宣传,加强对老年患者用药监测是以后药品不良反应工作的重点。

关 键 词:药品不良反应  分析  不合理用药

Retrospective Analysis of 502 Cases of Adverse Drug Reactions/Events
Li Gang,Huang Wenzhi,Long Enwu,Chen Min.Retrospective Analysis of 502 Cases of Adverse Drug Reactions/Events[J].Chinese Journal of Pharmacoepidemiology,2010(2):81-84.
Authors:Li Gang  Huang Wenzhi  Long Enwu  Chen Min
Institution:Li Gang~1,Huang Wenzhi~2,Long Enwu~1,Chen Min~1 1.Department of Pharmacy,Sichuan Provincial People\'s Hospital,Chengdu 610072,China,2.Center for ADR Monitoring of Sichuan Provincial
Abstract:Objective:To improve the monitoring level of adverse drug reactions(ADR),and provide the references for the rational use of drugs in the clinical practice.Method:502 ADR/ADE cases were collected in the whole year of 2008,which were analyzed retrospectively and evaluated in respect of age and sex,drug category,route of administration, severe ADR/ADEs and examples of irrational drug use.Result:48.21%patients in 502 cases of ADR/ADEs were more than 60 years old,and the antil-infective agents used by them accou...
Keywords:Adverse drug reactions  Analysis  Irrational drug use  
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