| 癫痫和热性惊厥患儿脑脊液生长抑素的变化 |
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| 引用本文： | 施旭来,李光乾,汤行录,叶秀云,陈翔,胡鸿文. 癫痫和热性惊厥患儿脑脊液生长抑素的变化[J]. 实用儿科临床杂志, 2005, 20(5): 464-465 |
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| 作者姓名： | 施旭来 李光乾 汤行录 叶秀云 陈翔 胡鸿文 |
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| 作者单位： | 温州医学院附属育英儿童医院神经内科 浙江温州325027(施旭来，李光乾，汤行录，叶秀云，陈翔)，温州医学院附属育英儿童医院神经内科 浙江温州325027(胡鸿文) |
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| 摘 要： | 目的探讨癞痫(EP)和热性惊厥(FC)患儿脑脊液(CSF)生长抑素(SS)含量及其与EP和FC发病机制关系。方法采用放射免疫法(RIA)测定EP和FC患儿CSF中SS含量。结果EP组CSF中SS水平(139.59±45.95)ng/L明显高于FC组(89.71±37.51)ng/L和对照组(77.31±37.10)ng/L(P均<0 05);FC组CSF中sS水平(89 71±37 51)ng/L与对照组比较无显著性差异(P>0.05);严重组EP和FC患儿CSF中SS水平与普通组比较均无显著性差异(P均>0.05)。结论SS参与EP发作,可能有致EP发作作用,而与FC的惊厥发作无关。
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| 关 键 词： | 癫痫 惊厥 热性 生长抑素 |
| 文章编号： | 1003-515X(2005)05-0464-02 |
| 修稿时间： | 2005-02-25 |
Changes of Somatostatin in Cerebrospinal Fluid in Children with Epilepsy and Febrile Convulsion |
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| SHI Xu - lai,LI Guang - qian,TANG Xing - lu,YE Xiu - yun,CHEN Xiang,HU Hong - wen. Changes of Somatostatin in Cerebrospinal Fluid in Children with Epilepsy and Febrile Convulsion[J]. Journal of Applied Clinical Pediatrics, 2005, 20(5): 464-465 |
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| Authors: | SHI Xu - lai LI Guang - qian TANG Xing - lu YE Xiu - yun CHEN Xiang HU Hong - wen |
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| Abstract: | Objective To study somatostatin (SS)in cerebrospinal fluid(CSF) and its relation with the pathogenesis in children with epilepsy(EP) and febrile convulsion(FC). Methods CSF SS levels in children with EP or FC were determined by R1A. Results CSF SS levels in EP group were significantly higher than those in FC group or in control group(P<0.05);the C'SF SS levels in FC group were higher than those in control group,but had no statistical difference(P>0.05);and the CSF SS levels in the severe EP or FC group were no significant difference with those in the common EP group( P >0.05), Conclusions It can be suggested that the CSF SS levels are significant increased after seizures in children with EP and that SS can cause seizures in children with EP but not in children with FC. |
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| Keywords: | epilepsy febrile convulsion somatostatin |
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