| AdeC基因与鲍曼不动杆菌耐药性的研究 |
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| 引用本文： | 沈况敏,周格红,赵珊珊,高笑宇,张萍.AdeC基因与鲍曼不动杆菌耐药性的研究[J].抗感染药学,2012,9(1):52-53. |
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| 作者姓名： | 沈况敏 周格红 赵珊珊 高笑宇 张萍 |
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| 作者单位： | 湖州师范学院医学院,创新实验室,浙江湖州313000 |
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| 基金项目： | 湖州师范学院学生科研重点项目(编号:xsky2011021) |
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| 摘 要： | 目的:探讨adeC基因与鲍曼不动杆菌耐药性的关系。方法:K-B法检测30株鲍曼不动杆菌对头孢曲松、利福平、亚胺培南、庆大霉素、环丙沙星5种抗菌药物的耐药性,采用PCR技术扩增adeC基因,观察30株鲍曼不动杆菌adeC基因携带情况。结果:30株鲍曼不动杆菌中,28株为耐药菌;耐药性鲍曼不动杆菌中adeC基因阳性率为96.43%(27/28)。结论:adeC基因是鲍曼不动杆菌耐药的重要机制之一。
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| 关 键 词： | 鲍曼不动杆菌 adeC基因 耐药 |
Study on AdeC Gene and Antibiotics Resistance in Acinetobacter baumanii |
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| SHEN Kuang-min
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ZHOU Ge-hong
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ZHAO Shan-shan
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GAO Xiao-yu
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ZHANG Ping.Study on AdeC Gene and Antibiotics Resistance in Acinetobacter baumanii[J].Anti-infection Pharmacy,2012,9(1):52-53. |
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| Authors: | SHEN Kuang-min ZHOU Ge-hong ZHAO Shan-shan GAO Xiao-yu ZHANG Ping |
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| Institution: | Innovation Laboratory, Medical School of Huzhou Normal College, Huzhou Zhejiang 313000, China |
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| Abstract: | Objective:To investigate the relationship between adeC gene and antibiotics resistance in Acinetobacter baumanii. Methods:The antibiotic resistance was tested by K-B method in Acinetobacter baumanii, and adeC gene was detected by PCR. Results: The antibiotic susceptibility was tested by K-B method in Acinetobacter baumanii, and adeC gene was detected by PCR. Results: In 30 strains of Acinetobacter baumanii,28 strains were resistant to antibiotics, and for those antibiotics resistant bacteria, the positive rate of adeC gene was 96.43%(27/28).Conclusion: The adeC gene is a cause of antibiotics resistance in Acinetobacter baumanii.27 strains carring adeC gene in 30 strains of Acinetobacter baumanii, and the positive rate was 90%. Conclusion: The adeC gene is a cause of antibiotics resistance in Acinetobacter baumanii. |
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| Keywords: | Acinetobacter baumanii adeC gene antibiotics resistance |
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