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化疗联合顺铂腹腔热灌注治疗25例中晚期卵巢癌术后的疗效分析
引用本文:肖巍,朱莉,高晓旭.化疗联合顺铂腹腔热灌注治疗25例中晚期卵巢癌术后的疗效分析[J].中国妇幼保健,2008,23(4):572-573.
作者姓名:肖巍  朱莉  高晓旭
作者单位:哈尔滨医科大学第四临床医学院,黑龙江,哈尔滨,150001
摘    要:目的:探讨中晚期卵巢癌术后的治疗方法及疗效。方法:以环磷酰胺静脉化疗联合顺铂腹腔热灌注治疗25例中晚期卵巢癌,观察其疗效及其副反应。结果:完全缓解(CR)4例,部分缓解(PR)14例,稳定(NC)5例,进展(PD)2例,总有效率72%。主要毒副反应为骨髓抑制。结论:化疗联合顺铂腹腔热灌注治疗对中晚期卵巢癌疗效较好,毒副反应较少。

关 键 词:中晚期卵巢癌  化疗  腹腔热灌注
文章编号:1001-4411(2008)04-0572-02
收稿时间:2006-08-16
修稿时间:2006年8月16日

Effetcs of DDP with cisplatin by CHPP on patients with late ovarian carcinoma
XIAO Wei,ZHU Li,GAO Xiao-Xu.Effetcs of DDP with cisplatin by CHPP on patients with late ovarian carcinoma[J].Maternal and Child Health Care of China,2008,23(4):572-573.
Authors:XIAO Wei  ZHU Li  GAO Xiao-Xu
Abstract:Objective:To study the treatment of late ovarian carcinoma.Methods:Twenty-five patients with advanced ovarian carcinoma were treated with CTX+DDP by continous hyperthermic peritoneal perfusion(CHPP).Results:CR in 4 cases,PR in 14,NC in 5 and PD in 2 were obtained with an overall response rate 72%.The majority toxitity was bone marrow depression.Conclusion:DDP with cisplatin by CHPP on patients with late ovarian carcinoma may be a safe and effective therapy.
Keywords:Late ovarian carcinoma  Chemotherapeutic treatment  Continous hyperthermic peritoneal perfusion(CHPP)
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