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1,6-二磷酸果糖治疗新生儿窒息并发缺氧缺血性脑病的研究
引用本文:何方. 1,6-二磷酸果糖治疗新生儿窒息并发缺氧缺血性脑病的研究[J]. 现代中西医结合杂志, 2003, 12(13): 1350-1351
作者姓名:何方
作者单位:河南省南阳卫校附属医院,河南,南阳,473058
摘    要:目的 观察 1,6-二磷酸果糖对新生儿窒息并发缺氧缺血性脑病 (HIE)的治疗作用。方法 将 2 0 2例HIE患儿随机分为 2组 ,治疗组给予 1,6-二磷酸果糖 ,对照组给予胞二磷胆碱治疗。结果 治疗组有效率为 96.2 % ,对照组有效率为 80 .6% ,两组比较有显著性差异(P <0 .0 5 )。结论  1,6-二磷酸果糖治疗新生儿HIE有效率高 ,神经系统后遗症少 ,且无明显的副作用

关 键 词:窒息  新生儿  缺氧缺血性脑病  1,6-二磷酸果糖  胞二磷胆碱
文章编号:1008-8849(2003)13-1350-02
修稿时间:2002-11-30

Study of fructose-1, 6-diphosphate on hypoxic ischemic encephalopathy of asphyxia neonatorum
HE Fang. Study of fructose-1, 6-diphosphate on hypoxic ischemic encephalopathy of asphyxia neonatorum[J]. Modern Journal of Integrated Chinese Traditional and Western Medicine, 2003, 12(13): 1350-1351
Authors:HE Fang
Abstract:Objective It is to evaluate the effect of fructose-1, 6-diphosphate on hypoxic ischemic encephalopathy (HIE) of asphyxia neonatorum. Methods 202 infants with HIE were divided into two groups at random. Treatment group were treated with fructose-1, 6-diphosphate and control group were treated with citicoline. Results Effective rate of treatment group was 96.2% and that of control group was 80.6%. There was significantly difference betweem two groups (P<0.05). Conclusion With high effective rate, seldom sequela of nervous system and without obvious side effect, fructose-1, 6-diphosphate is effective on HIE of asphyxia neonatorum.
Keywords:asphyxia  neonatus  hypoxic ischemic encephalopathy  fructose-1   6-diphosphate  citicoline
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