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Developmental changes rather than repeated administration drive paracetamol glucuronidation in neonates and infants
Authors:Elke H. J. Krekels  Saskia van Ham  Karel Allegaert  Jan de Hoon  Dick Tibboel  Meindert Danhof  Catherijne A. J. Knibbe
Affiliation:1. Division of Pharmacology, Leiden Academic Center for Drug Research, Leiden, The Netherlands
2. Department of Development and Regeneration, KU Leuven, Leuven, Belgium
3. Neonatal Intensive Care Unit, University Hospitals, Leuven, Belgium
4. Center for Clinical Pharmacology, University Hospitals, Leuven, Belgium
5. Intensive Care and Department of Pediatric Surgery, Erasmus MC-Sophia Children’s Hospital, Rotterdam, The Netherlands
6. Department of Clinical Pharmacy, St. Antonius Hospital, PO Box 2500, 3430 EM, Nieuwegein, The Netherlands
Abstract:
Keywords:
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