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声学造影评价兔腹主动脉粥样硬化的初步研究
引用本文:李馨,高云华,谭开彬,司良毅,刘平. 声学造影评价兔腹主动脉粥样硬化的初步研究[J]. 中国医学影像技术, 2004, 20(11): 1680-1682
作者姓名:李馨  高云华  谭开彬  司良毅  刘平
作者单位:1. 第三军医大学西南医院老年病科,重庆,400038
2. 第三军医大学新桥医院超声科
摘    要:目的探讨超声造影在动脉粥样硬化中的诊断价值.方法新西兰大白兔5只,高脂饮食喂养12周建立动脉粥样硬化模型.模型建立前后应用自制的脂膜氟碳声学造影剂"脂氟显"行腹主动脉超声造影.造影前后分别采用二维成像、视觉评分和视频密度法监测兔腹主动脉内膜、粥样斑超声成像特征并作定量分析.结果造影后血管内膜、粥样斑回声明显增强,视频密度较造影前明显增加.结论造影剂可提高血管内膜分辨率及粥样斑检出率,在动脉粥样硬化的早期诊断中有重要应用价值.

关 键 词:声学造影  动脉粥样硬化  腹主动脉
文章编号:1003-3289(2004)11-1680-03
收稿时间:2004-04-10
修稿时间:2004-04-10

Enhanced ultrasonography of atherosclerosis of abdominal aorta in rabbit model: a preliminary study
LI Xin,GAO Yun-hu,TAN Kai-bin,SI Liang-yi and LIU Ping. Enhanced ultrasonography of atherosclerosis of abdominal aorta in rabbit model: a preliminary study[J]. Chinese Journal of Medical Imaging Technology, 2004, 20(11): 1680-1682
Authors:LI Xin  GAO Yun-hu  TAN Kai-bin  SI Liang-yi  LIU Ping
Affiliation:Gerontology Division, Southwest Hospital, Third Military Medical University, Chongqing 400038, China;Gerontology Division, Southwest Hospital, Third Military Medical University, Chongqing 400038, China
Abstract:Objective To discuss the value of enhanced ultrasonography in monitoring atherosclerosis. Methods Five New Zealand rabbits were fed with cholesterol diet for 12 weeks in order to create the animal model of atherosclerosis. The images for abdominal aorta were obtained continuously after intravenous injection of self-made microbubbles (ZhiFuXian). The videointensity of intima and plaque were compared with those without contrast agent. Results Significant increases for intima and plaque videointensity were observed after microbubbles injection. Conclusion Enhanced ultrasonography is very effective for sonography improvement in detecting early atherosclerosis. [
Keywords:Enhanced ultrasonography  Atherosclerosis  Abdominal aorta
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