肠道病毒71型IgM阳性手足口病患儿70例心肌酶谱的临床观察

目的了解肠道病毒71型（EV71）IgM阳性手足口病患儿心肌酶谱的改变及其临床意义。方法对我市2009年3—4月收治的EV71IgM阳性的足口病患儿进行心肌酶谱：天门冬氨酸氨基转移酶（AST）、乳酸脱氢酶（LDH）、肌酸激酶（CK）、肌酸激酶同工酶（CK—MB）进行检测并分析其临床意义。结果70例EV71IgM阳性手足口病患儿有66例有一项或多项心肌酶谱异常，占94．3％；其中CK～MB单项异常24例，占34．28％；LDH、CK—MB两项项异常25例，占35．71％；CK、CK—MB两项项异常5例，占7．14％；AST、LDH、CK、CK—MB四项项异常5例，占7．14％：LDH、CK、CK—MB三项异常6例，占8．6％；AST、LDH、CK—MB三项异常1例，占1．42％；四项全正常者4例，占5．7％。结论EV71IgM阳性手足口病患儿大部分心肌酶谱异常，可能存在心肌损害。

Clinical observation on serum myocardial enzymes in children with enterovirus 71 IgM positive hand-foot-mouth disease.

Objective To analyze changes of serum myocardial enzymes in children with Enterovirus 71 IgM positive patients suffered with hand-foot-mouth disease(HFMD).Methods Serum myocardial enzymes and electrocardiogram in 70 cases with Enterovirus 71 IgM positive HFMD were examined.Myocardial enzymes included aspartate aminotransferase(AST),lactate dehydrogenase(LDH),creatine kinase(CK) and isoenzymes of creatine kinase(CK-MB).Results In 70 cases,66(94.3%) had one or more kinds of abnormal myocardial enzyme levels i...