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细胞紧密连接蛋白与乳腺癌侵袭转移相关性研究的现状分析
引用本文:韩雪,张文海.细胞紧密连接蛋白与乳腺癌侵袭转移相关性研究的现状分析[J].中华肿瘤防治杂志,2011,18(8):633-636.
作者姓名:韩雪  张文海
作者单位:中国医科大学附属盛京医院乳腺外科,辽宁沈阳,110004
摘    要:目的:总结国内外关于细胞间紧密连接的破坏在乳腺癌浸润与转移中的作用.方法:应用Medline及CNKI期刊全文数据库系统以"乳腺癌、转移和紧密连接"为关键词检索1997-2010年的相关文献,分析文献30篇.纳入标准:1)乳腺癌的转移机制;2)紧密连接的结构及功能;3)紧密连接的破坏与乳腺癌转移的相关性.结果:紧密连接...

关 键 词:乳腺肿瘤  肿瘤转移  综述文献

Status analysis of the significance of tight junction in the invasion of breast cancer
HAN Xue,ZHANG Wen-hai.Status analysis of the significance of tight junction in the invasion of breast cancer[J].Chinese Journal of Cancer Prevention and Treatment,2011,18(8):633-636.
Authors:HAN Xue  ZHANG Wen-hai
Institution:HAN Xue,ZHANG Wen-haiDepartment of Breast Surgery,Shengjing Hospital of China Medical University,Shenyang 110004,P.R.Chin
Abstract:OBJECTIVE:To evaluate the close relationship with the breakdown of tight junction in the leading edge of cancer cells and invasion in breast cancer through literature review.METHODS:The papers published from 1997 to 2010 were searched from Medline and CNKI with the keywords breast cancer,metastasis and tight junction respectively or combinedly.Retrieval criteria:1) the metastasis mechanism of the breast cancer;2) the structure and function of tight junction;3) the relationship with tight junction and breast...
Keywords:breast neoplasms  neoplasms metastasis  review literature  
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