高龄患者在冠状动脉支架植入术后抗凝的临床观察

目的 评价以口服肠溶阿司匹林和氯吡格雷联用肝素静脉滴注的抗凝方案，在高龄患者冠状动脉支架术后应用的疗效及不良反应。方法 超过或等于70岁的高龄组患者63例，均在冠状动脉支架术后使用上述的抗凝方案。观察出血并发症及冠状动脉内血栓形成的发生率。结果 出现皮下出血2例，尿路出血2例，发生出血并发症的比例为6.2％。冠状动脉内血栓形成的1例（1.6％）。结论 高龄患者冠状动脉支架术后可以采用口服肠溶阿司匹林和氯吡格雷伍用肝素静脉滴注的抗凝方案。

Study of effectiveness and security in the elderly patients with anticoagulant therapy after coronary stenting

objectives To investigate the effectiveness in elder patients with anticoagulant therapy which composed of enteric-coated capsule aspirin, clopidogrel and heparin after implanting coronary stents. Methods Sixty-three patients over 70 years received anticoagulant therapy after implanting stents. Bleeding complications and stent thrombosis were compared in two groups. Results Two patients had subcutaneous hemorrhage, two patients and urinary hemorrhage and the bleeding complication rate was 6.2%. One patient had stent thrombosis (1.6%). Conclusions The anticoagulalant therapy used aspirin, clopidogrel and heparin is safe and effective in patients over 70 years after implanting coronary stents.