| 复方羊连胶囊质量标准研究 |
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| 引用本文： | 李鑫.复方羊连胶囊质量标准研究[J].中国药学杂志,2009,44(11):866-869. |
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| 作者姓名： | 李鑫 |
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| 作者单位： | 哈尔滨商业大学药学院 哈尔滨 150076 |
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| 摘 要： | 目的建立复方羊连胶囊的质量标准。方法采用TLC定性鉴别复方羊连胶囊中的黄连、丹参,采用RP-HPLC定量检测淫羊藿苷的含量。结果在TLC中分别检出黄连、丹参,斑点清晰可见,重现性好。利用RP-HPLC得到的淫羊藿苷的线性范围为4.4×10-2～4.4×10-1μg,r=0.9999;平均回收率为99.7%,RSD=1.05%(n=6)。结论定性定量方法简便、专属、准确,能有效地控制复方羊连胶囊的质量。
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| 关 键 词： | 薄层色谱法 淫羊藿苷 反向高效液相色谱法 |
| 收稿时间： | 2008-12-22; |
Studies on Quality Standard of Compound Yanglian Capsule |
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| LI Xin.Studies on Quality Standard of Compound Yanglian Capsule[J].Chinese Pharmaceutical Journal,2009,44(11):866-869. |
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| Authors: | LI Xin |
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| Institution: | School of Pharmacy，Harbin Commercial University，Harbin 150076，China |
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| Abstract: | OBJECTIVE To establish the quality standard of Compound Yanglian capsule.METHODS TLC was used to identify the rhizome of Chinese goldthread and Radix Salviae Miltiorrhizae in Compound Yanglian capsule.RP-HPLC was used to determine the content of icraiine.RESULTS The rhizome of Chinese goldthread and Radix Salviae Miltiorrhizae in Compound Yanglian capsule was found on TCL.The spot was clear.The method showed a good reproducibility.The Linear Range of icraiine was in the range of 4.4×10-2-4.4×10-1 μg,r=0.999 9.The average recovery rate is 99.7% with RSD of 1.05%(n=6).CONCLUSION The method is simple,efficient,sensitive and can be applied to quality control of Compound Yanglian capsules. |
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| Keywords: | TLC icraiine RP-HPLC |
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