小飞蓬化学成分的研究

 目的研究小飞蓬的化学成分。方法应用溶剂法进行提取,采用硅胶柱色谱和凝胶柱色谱Sephadex LH-20进行分离纯化,通过理化方法和波谱数据分析进行结构鉴定。结果从体积分数70%乙醇提取物中分离并鉴定了12个化合物,分别为α-香树脂醇(Ⅰ)、β-香树脂醇(Ⅱ)、β-谷甾醇(Ⅲ)、表木栓醇(Ⅳ)、齐墩果酸(Ⅴ)、菠甾醇-3-O-葡萄糖苷(Ⅵ)、3,5,7,3′,4′-五羟基黄酮(Ⅶ)、槲皮素-3-O-α-L-鼠李糖苷(Ⅷ)、芦丁(Ⅸ)、野黄芩苷(Ⅹ)、黄芩苷(Ⅺ)、绿原酸(Ⅻ)。结论12个化合物均为首次从该植物中分离得到。

Chemical Constituents of Erigeron canadensis

OBJECTIVE To study the chemical components from Erigeron canadensis. METHODS The isolation and purification were carried out on silica gel column and Sephadex LH-20. The structures were elucidated on the basis of chemical evidences and spectral analysis. RESULT Twelve compounds were isolated and their structures were identified as αasamyrin(Ⅰ), β-amyrin (Ⅱ), β-sitosterol(Ⅲ)、epifriedelinol(Ⅳ), oleanolic acid(Ⅴ), spinasterol-3-O-β-D-glucopyranoside(Ⅵ), 3,5, 7,3′,4′-pentahydroxyflavone(Ⅶ), quercetin-3-O-α-L-rhamnose(Ⅷ), rutin(Ⅸ), scutellarin(Ⅹ), baical(iⅪ) and chlorogenic acid(Ⅻ). CONCLUSION All the twelve compunds are isolated from the title plant for the first time.