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Allergic hypersensitivity to topical and systemic corticosteroids: a review |
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| Authors: | M Baeck L Marot J-F Nicolas C Pilette D Tennstedt A Goossens |
| Institution: | Department of Dermatology, Cliniques Universitaires Saint-Luc, UniversitéCatholique de Louvain, Brussels, Belgium;;Department of Immuno-Allergology, University Hospital Centre Lyon Sud, Hospices Civiles de Lyon, Lyon, France;;Department of Pneumology, Cliniques Universitaires Saint-Luc, UniversitéCatholique de Louvain, Brussels;;Department of Dermatology, University Hospital, Katholieke Universiteit Leuven, Leuven, Belgium |
| Abstract: | Corticosteroids, which are potent anti-inflammatory and immunomodulator agents used in the treatment of various inflammatory diseases including allergic diseases, can in some cases produce immediate or delayed hypersensitivity reactions. This review summarizes the epidemiological and clinical characteristics of such reactions, including related diagnostic issues. It also presents a detailed analysis of the proposed immunological mechanisms including underlying cross-reactions. |
| Keywords: | allergic contact dermatitis corticosteroid cross-reactions delayed hypersensitivity immediate hypersensitivity |