Reactivation of Q fever following cardiac surgery |
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Authors: | T J Marrie J Cunning P Durnford |
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Institution: | (1) Department of Medicine, Dalhousi University and Victoria General Hospital, 1278 Tower Road, B3H 2Y9 Halifax, Nova Scotia, Canada;(2) Department of Microbiology, Dalhousi University and Victoria General Hospital, 1278 Tower Road, B3H 2Y9 Halifax, Nova Scotia, Canada |
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Abstract: | To determine whether reactivation of Q fever occurs following cardiac surgery 43 patients who had antibodies toCoxiella burnetii were identified pre-operatively. Serum samples were collected 1, 4 to 6, and 24 weeks post-operatively. One patient had active Q fever endocarditis. Seven of the remaining 42 (17 %) had a fourfold rise in titres for antibodies toCoxiella burnetii post-operatively. Only two of these seven had an increase in antibody titres for other agents suggesting that the fourfold titre rise forCoxiella burnetii was not part of a polyclonal response. It is concluded that self-limited reactivation of infection may occur amongCoxiella burnetii seropositive patients undergoing open heart surgery. |
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