Usefulness of C-reactive protein as a marker of early post-infarct left ventricular systolic dysfunction |
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| Authors: | Iwona Swiatkiewicz Marek Kozinski Przemyslaw Magielski Joanna Gierach Tomasz Fabiszak Aldona Kubica Adam Sukiennik Eliano Pio Navarese Grazyna Odrowaz-Sypniewska Jacek Kubica |
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| Institution: | Department of Cardiology and Internal Medicine, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, 9 Sklodowskiej-Curie Street, 85-094 Bydgoszcz, Poland. i.swiat@wp.pl |
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| Abstract: | Objective To assess the usefulness of in-hospital measurement of C-reactive protein (CRP) concentration in comparison to well-established risk factors as a marker of post-infarct left ventricular systolic dysfunction (LVSD) at discharge. Materials and methods Two hundred and four consecutive patients with ST-segment-elevation myocardial infarction (STEMI) were prospectively enrolled into the study. CRP plasma concentrations were measured before reperfusion, 24?h after admission and at discharge with an ultra-sensitive latex immunoassay. Results CRP concentration increased significantly during the first 24?h of hospitalization (2.4?±?1.9 vs. 15.7?±?17.0?mg/L; p?p?p?p?p?Conclusion Measurement of CRP plasma concentration at discharge may be useful as a marker of early LVSD in patients after a first STEMI. |
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