小儿轮状病毒肠炎合并心肌损害高危因素的探讨

目的探讨轮状病毒肠炎合并心肌损害的高危因素。方法选择肌酸激酶同工酶≥48 IU/L的轮状病毒肠炎的患儿215例。对可能的危险因素:性别、年龄、有无发热、脱水程度、有无酸中毒、有无电解质紊乱、腹泻次数先进行单因素分析,然后对单因素分析有显著意义的因素做多因素Logistic回归分析。结果单因素分析显示:达到显著水平的高危因素为年龄及有无酸中毒。多因素Logistic回归分析显示:只有年龄≤1岁是小儿轮状病毒肠炎合并心肌损害的高危因素。结论年龄≤1岁是小儿轮状病毒肠炎合并心肌损害的高危因素,年龄越小的轮状病毒肠炎患儿在注意脱水、酸中毒的同时还要注意有无心肌损害,特别是小于1岁的患儿,及时给予保护营养心肌治疗,避免发生严重后果。

Approach on high risk factor of children with rotavirus enteritis combined with cardiac damage

Objective It is to approach the high risk factor of rotavirus enteritis combined with cardiac damage.Methods Two hundred and fifteen children with rotavirus enteritis who were in hospital and whose isoenzyme of creatine kinase(CK-MB)≥48 IU/L were chosen.First,the probable risk factors such as sex,age,whether or not fever,degree of dehydration,whether or not acidosis,whether or not electrolyte disturbances and the frequency of diarrhea were undergone single factor analysis.Then the significant factors in single factor analysis were undergone multiple factor Logistic regression analysis.Results Single factor analysis showed that the significant high risk factors were age and whether or not acidosis.Multiple factor Logistic regression analysis showed that only age≤1 year old was the high risk factor of children with rotavirus enteritis combined with cardiac damage.Conclusion Age≤1 year old is the high risk factor of children with rotavirus enteritis combined with cardiac damage.The smaller age of the children with rotavirus enteritis,the more necessary attention need to pay to whether or not cardiac damage when the dehydration and acidosis are paid attention to,especially the children whose ages were≤1 year old.Protecting and nutrition on the cardiac muscle could be supplied in time to avoid the serious consequence.