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酶免疫分析法体外检测过敏原在荨麻疹病因筛查中的价值
引用本文:谷梅,顾有守,张书岭,钟山,黄进梅,潘慧清.酶免疫分析法体外检测过敏原在荨麻疹病因筛查中的价值[J].中国麻风皮肤病杂志,2004,20(5):443-444.
作者姓名:谷梅  顾有守  张书岭  钟山  黄进梅  潘慧清
作者单位:1. 广东省皮肤性病防治中心,510500
2. 深圳市第二人民医院,518035
摘    要:目的 : 评价酶免疫分析法 (ELISA)体外检测过敏原在荨麻疹病因筛查中的临床应用价值。方法 : 采用ELISA检测 15 4例荨麻疹患者和 11例健康对照者血清食入性及吸入性过敏原特异性IgE。结果 :  15 4例荨麻疹患者总阳性率为 6 8.8% ,明显高于健康对照组 9.1%的阳性率 (P <0 .0 1)。其中食入组阳性率为 4 4 .8% ,鳕 (带鱼、金枪鱼 )阳性率最高 ,螃蟹、虾、龙虾次之。吸入组阳性率 4 8.1% ,尘 (粉 )螨阳性率最高 ,屋尘次之。结论 : ELISA体外检测过敏原在荨麻疹病因筛查中具有实际应用价值。

关 键 词:荨麻疹  过敏原  阳性率  体外检测  筛查  病因  患者  酶免疫分析法  ELISA  健康

Value of allergen detection in vitro by ELISA in aetiological screening of urticaria
Gu Mei,Gu Youshou,Zhang Shuling,et al..Value of allergen detection in vitro by ELISA in aetiological screening of urticaria[J].China Journal of Leprosy and Skin Diseases,2004,20(5):443-444.
Authors:Gu Mei  Gu Youshou  Zhang Shuling  
Institution:Gu Mei,Gu Youshou,Zhang Shuling,et al. Guangdong Institute of Dermatovenereology,Guangzhou,510500
Abstract:Objective: To evaluate the clinical value of in vitro allergen detection by ELISA in aetiological screening of urticaria. Methods: The specific IgE for food and inhalant allergens were detected serologically by ELISA in the sera from 154 cases of urticaria and 11 healthy controls. Results: Out of 154 cases of urticaria examined, total positivity rate was 68.8%, compared with that of 9.1% in control group. There was a significant difference between the two groups (P<0.01). The food allergens were found among 44.8% of patients, mainly including cod (hairtail, tuna) and crab, shrimp and lobster. The inhalant allergens were found among 48.1% of patients, mainly including dust (powder) mite and house dust. Conclusion: Detection of in vitro allergen by ELISA is of great importance in aetiological screening of urticaria.
Keywords:allergen  ELISA  urticaria  
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