| Abstract: | A new method of retinal detachment simulation includes subretinal administration of ferromagnetic fluid with subsequent action from without by a permanent magnetic field. Retinal detachment was induced in 24 eyes of experimental animals. Of them, clinical picture of total high fibrous detachment of the retina was simulated in 16 eyes, and high rigid detachment occupying 2-3 quadrants of the eye fundus--in 8 eyes. Histologically, the induced retinal detachment was characterized by development of degenerative-proliferative processes in all eye coats. The proposed model allows to obtain different variants of "fresh" and "old" retinal detachments. It is highly reproducible, creates conditions for studying all aspects of pathogenesis of complicated forms of retinal detachment and for development of methods for its treatment. |
