妊娠期糖尿病孕妇胰岛素联合阿司匹林治疗的有效性分析

目的探讨分析妊娠期糖尿病孕妇胰岛素联合阿司匹林治疗的有效性。方法在2019年3月—2020年3月将该院收治的106例妊娠期糖尿病孕妇按照双色球分组法分为两组,对照组53例单纯采用胰岛素治疗,观察组53例联合应用胰岛素、阿司匹林治疗,获取两组治疗相关数据,并进行对比分析。结果治疗前两组糖化血清白蛋白、糖化血红蛋白、空腹血糖水平比较,差异无统计学意义(P>0.05);治疗后观察组糖化血清白蛋白(13.02±3.01)mmol/L、糖化血红蛋白(5.24±0.78)%、空腹血糖(5.36±0.67)mmol/L低于对照组(16.89±2.34)mmol/L、(6.68±0.91)%、(6.79±0.73)mmol/L,差异有统计学意义(t=7.390、8.747、10.507,P<0.05)。观察组的早产率11.32%、剖宫产率15.10%、高血压率11.32%、子痫前期率11.32%、新生儿低血糖率9.43%、巨大儿率9.43%、新生儿黄疸率11.32%、新生儿呼吸窘迫率11.32%小于对照组28.30%、39.60%、28.30%、26.42%、28.30%、24.53%、28.30%、32.08%,差异有统计学意义(χ²=4.810、8.022、4.810、3.944、6.163、4.283、4.810、6.719,P<0.05)。结论妊娠期糖尿病孕妇采用胰岛素、阿司匹林治疗,可有效改善患者的血糖水平,可改善孕妇的妊娠结局,可减少新生儿不良事件,值得推广应用。

Analysis of the Effectiveness of Insulin Combined with Aspirin in Pregnant Women with Gestational Diabetes

Objective To explore and analyze the effectiveness of insulin combined with aspirin in pregnant women with gestational diabetes.Methods From March 2019 to March 2020,106 pregnant women with gestational diabetes mellitus admitted to the hospital were divided into two groups according to the two-color ball grouping method.The control group 53 cases were treated with insulin alone,and the observation group 53 cases were treated with insulin and aspirin.Obtain treatment-related data of the two groups and conduct comparative analysis.Results Before treatment,there was no significant difference in the levels of glycosylated serum albumin,glycosylated hemoglobin,and fasting blood glucose between the two groups(P>0.05);after treatment,the observation group’s glycosylated serum albumin(13.02±3.01)mmol/L,glycosylated hemoglobin(5.24±0.78)%,fasting blood glucose(5.36±0.67)mmol/L is lower than the control group(16.89±2.34)mmol/L,(6.68±0.91)%,(6.79±0.73)mmol/L,the difference is statistically significant(t=7.390,8.747,10.507,P<0.05).The rates of premature delivery,cesarean delivery,hypertension,preeclampsia,neonatal hypoglycemia,macrenia,jaundice and neonatal respiratory distress in the observation group were 11.32%,15.10%,11.32%,11.32%,9.43%,9.43%,11.32%and 11.32%,respectively,lower than those in the control group.The difference was statistically significant(χ²=4.810,8.022,4.810,3.944,6.163,4.283,4.810,6.719,P<0.05).Conclusion The treatment of insulin and aspirin in pregnant women with gestational diabetes can effectively improve the blood glucose level of the patients,improve the pregnancy outcome of the pregnant women,and reduce the adverse events of the newborn.It is worthy of promotion and application.