单孔胸腔镜解剖性肺段切除术与肺叶切除术对早期非小细胞肺癌患者近远期疗效分析

目的：探讨分析单孔腹腔镜解剖性肺段切除术与肺叶切除术对早期非小细胞肺癌患者近远期临床疗效。方法：回顾性分析2013年3月~2015年2月在我院采取单孔全胸腔镜治疗的早期非小细胞肺癌86例患者临床资料，其中行解剖性肺段切除术患者35例作为观察组、行肺叶切除术患者51例作为对照组，对比分析两组患者住院期间相关指标、术后1年肺功能指标减少比率（包括用力肺活量（FVC）、一秒用力呼气容积（FEV1）以及每分钟最大通气量（MVV）），并分析两组患者术后3年随访无进展生存时间。结果：观察组患者手术时间明显长于对照组（P<0.05），但观察组患者术后住院时间以及术后并发症明显低于对照组（P<0.05），两组术中出血量及住院费用无显著差异（P>0.05）。观察组患者术后1年肺功能指标下降比率显著低于对照组（P<0.05）。两组患者术后随访无进展生存时间无显著差异（P>0.05）。结论：单孔胸腔镜解剖性肺段切除术与肺叶切除术治疗早期非小细胞肺癌比较，手术更为复杂，但患者术后恢复快、并发症少，且两种手术方式对患者术后远期无进展生存时间无影响。

Analysis of short-term and long-term outcomes of single port thoracoscopic anatomic segmental resection and lobectomy for early stage non-small cell lung cancerSheng Yu Pan Yiping Zhao Jianming Sun Jun Zhejiang Jinhua Guangfu Tumor Hospital Department of thoracic surgery 321000

Objective: to investigate the short-term and long-term clinical efficacy of single port laparoscopic anatomical segmental resection and lobectomy for early stage non-small cell lung cancer. Methods: a retrospective analysis of the clinical data of 86 patients with early non small cell lung cancer treated by single hole total thoracoscopy from March 2013 to February 2015, was reviewed. 35 cases of dissected segmental resection were used as observation group and 51 patients with lobectomy as control group. The related indexes of the two groups were compared and analyzed. After 1, your lung function index reduction rate was analyzed, and the progression free survival time of the two groups was analyzed. Results: the operation time of the observation group was significantly longer than that of the control group (P<0.05), but the time of hospitalization and postoperative complications in the observation group were significantly lower than that of the control group (P<0.05). There was no significant difference in the amount of bleeding and the cost of hospitalization in the two groups (P>0.05). The decrease rate of pulmonary function index in the observation group 1 years after operation was significantly lower than that in the control group (P<0.05). There was no significant difference in the progression free survival time between the two groups (P>0.05). Conclusion: the operation is more complicated than the single hole thoracoscopic dissection and lobectomy for early non small cell lung cancer, but the postoperative recovery is faster and the complications are less, and the two surgical methods have no effect on the long-term free survival time of the patients.