微脉冲激光或传统格栅光凝联合康柏西普治疗糖尿病黄斑水肿的临床分析

目的 观察微脉冲激光或传统格栅光凝联合康柏西普治疗糖尿病黄斑水肿(DME)的有效性、安全性.方法 纳入2017年1月—2019年6月DME患者98眼,577 nm阈值下微脉冲联合治疗(A组)32眼、传统格栅光凝联合治疗(B组)30只眼、单纯康柏西普治疗(C组)36眼.观察最佳矫正视力(BCVA)、黄斑中心凹厚度(CFT...

Clinical Analysis of Micropulse Laser or Traditional Grid Photocoagulation Combined with Conbercept in the Treatment of Diabetic Macular Edema

Objective To observe the effectiveness and safety of micropulse laser or traditional grid photocoagulation combined with Conbercept in the treatment of diabetic macular edema(DME).Methods From January 2017 to June 2019,98 eyes of DME patients were enrolled,32 eyes were treated with micropulse at 577nm threshold(group A),30 eyes were treated with traditional grid photocoagulation(group B),and only CompaXil General treatment(group C)36 eyes.Observe the best corrected visual acuity(BCVA),macular foveal thickness(CFT),macular volume(MV),changes in the microstructure of the retina and the number of injection needles.Results The BCVA,CFT,and MV of all patients at 3,6,9,12 months after treatment were improved compared to before,and the difference was statistically significant(F=39.558,62.901,10.078,P<0.001).Compared between groups,the difference was not statistically significant(F=0.417,0.085,0.061,P=0.513,0.675,0.823).The average annual drug injections times in groups A and B were(6.3±0.9)times and(6.5±1.1)times lower than those in group C(8.6±2.2)times,respectively.The difference was statistically significant(F=7.980,P<0.05).Laser damage was seen in group B but not in group A.Conclusion Both laser combination therapy and drug therapy alone are effective for DME.Combined therapy can reduce the number of drug injections;micropulse laser is safer than traditional grid photocoagulation.