血脂康辛伐他汀治疗2型糖尿病并血脂异常

目的 比较血脂康与辛伐他汀治疗2型糖尿病（DM）并血脂异常的临床疗效。方法 2型DM并血脂异常患者89例，分A组（血脂康组）及B组（辛伐他汀组）分别测定两组患者服药前及服药后3个月的空腹血糖（FG）、餐后2h血糖（2hPG）、空腹胰岛素（Fins）、血胆固醇（TC）、甘油三脂（TG）、低密度脂蛋白胆固醇（LDL—c）、高密度脂蛋白胆固醇（HDL—C）水平，并进行比较。结果 两组患者的血TC、TG、LDL—C都较服药前降低，HDL—C水平较服药前升高，差异有显著意义。A组空腹血糖、餐后血糖明显较服药前降低，差异有显著意义，B组空腹血糖、餐后血糖较服药前降低，但差异无显著意义。两组的胰岛素敏感指数（IAI）都较服药前提高，但A组较明显（P〈0．05），B组不明显（P〉0．05）。结论 血脂康与辛伐他汀都有明显的调节血脂作用，血脂康还有协助降糖及提高胰岛素敏感性作用。

Comparison of Effects between Xuezhikang and Simvastatin on Type 2 DM with Dyslipidosis

Objective To study the treatment effects of Xuezhikang on type 2 DM patients with dyslipidosis and to compare it with simvastatin.Methods 89 cases type2 DM patients with dyslipidosis were divided into group A(n=46,Xue zhikang 0.6g,bid,p.o) and group B(n=43,Simvastatin 20mg,qh,p.o) The changes of their fasting glucose(FG),2-hour postprandial blood glucose(2-hPG),fasting insulin(FIns),serum total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C) were observed before and three months after treatment.Results The serum TC,TG,LDL-C of two groups decreased significantly,and HDL-C of two groups increased significantly.FG and 2hPG of group A decreased significantly.IAI(Insulin) of group A increased significantly(P<0.05),group B not significantly(P>(0.05)).Conclusion Both Xuezhikang and Simvastatin can effectively adjust dyslipidosis.Xuezhikang can help reduce blood glucose and increase the sensibility of insulin in type2DM patients.