| 免疫调节剂治疗炎症性肠病的监测 |
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| 引用本文： | 顾清,欧阳钦.免疫调节剂治疗炎症性肠病的监测[J].国际消化病杂志,2007,27(1):41-44. |
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| 作者姓名： | 顾清 欧阳钦 |
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| 作者单位： | 610041,四川大学华西医院消化内科 |
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| 摘 要： | 自上世纪九十年代以来,免疫调节剂已成为炎症性肠病(IBD)系统治疗的重要组成部分,尤以硫唑嘌呤(AZA)、6-巯基嘌呤(6-MP)、环孢素A(CsA)、甲氨蝶呤(MTX)应用最广泛.使用免疫调节剂可能出现强烈而明显的不良反应,用药时应仔细监测.此文主要就AZA、6-MP、CsA、MTX治疗炎症性肠病的监测及不良反应作一综述.
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| 关 键 词： | 炎症性肠病 免疫调节剂 监测 不良反应 |
| 修稿时间： | 2006-04-26 |
Monitoring of immunomodulators in inflammatory bowel disease |
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| GU Qing,OUYANG Qin.Monitoring of immunomodulators in inflammatory bowel disease[J].International Journal of Digestive Disease,2007,27(1):41-44. |
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| Authors: | GU Qing OUYANG Qin |
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| Institution: | Department of Gastroenterology, West China Hospital, Sichuan University ,Chen gdu (610041 |
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| Abstract: | Treatment of inflammatory bowel disease(IBD) commonly requires utilization of immunodulatory medications. The most commonly immunomodulators used for treatment of IBD are azathioprine,6-mercaptopurine,cyclosporine and metho- trexate.Great care must be taken in monitoring patients who receive these medications to reduce the risk of side-effects and toxicity.This review will provide information on monitoring of metabolites and the adverse reactions profile for each medica- tion. |
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| Keywords: | Inflammatory bowel disease Immunomodulator Monitoring Adverse reactions |
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