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mRNA expression analysis of cell cycle genes in islets of pregnant mice |
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| Authors: | A Schraenen G de Faudeur L Thorrez K Lemaire G Van Wichelen M Granvik L Van Lommel P in’t Veld F Schuit |
| Institution: | (1) Gene Expression Unit, Department of Molecular Cell Biology, Katholieke Universiteit Leuven, Herestraat 49, mailbox 901, 3000 Leuven, Belgium;(2) Department of Electrical Engineering, ESAT-SCD, Katholieke Universiteit Leuven, Leuven, Belgium;(3) Center for Computational Systems Biology, SymBioSys, Katholieke Universiteit Leuven, Leuven, Belgium;(4) Department of Pathology, Vrije Universiteit Brussel, Brussels, Belgium; |
| Abstract: | Aims/hypothesisPregnancy requires an increase in the functional beta cell mass to match metabolic needs for insulin. To understand this adaptation at the molecular level, we undertook a time course analysis of mRNA expression in mice. |
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