神经性厌食症患者生命质量的初步研究

目的 探讨神经性厌食症患者的生命质量.方法 使用SF-36健康评定量表对49名神经性厌食症患者的健康相关生命质量进行测评.结果 AN组SF-36量表分值与正常人群相比,在生理职能(RP)、总体健康(GH)、社会功能(SF)、情感职能(RE)和精神健康(MH)维度分数(44.4±36.2)分,(53.3±16.3)分,(56.6±24.1)分,(45.6±38.9)分,(47.5±21.4)分]均低于普通人群,而且均差异有显著性(P<0.01).长病程组患者SF-36量表各维度平均分数均低于短病程患者,且在生理功能(PF)(85.5±13.4)分,(93.2±6.6)分]、躯体疼痛(BP)(74.0±20.3)分,(87.2±14.7)分]、总体健康(GH)(45.8±14.7)分,(57.5±15.7)分]及总分(93.5±14.4)分,(104.5±13.6)分]差异有显著性(P<0.05).结论 神经性厌食症患者的生命质量较正常人群差,病程越长,生命质量越低.

A pilot study on quality of life in anorexia nervosa

Objective The health-related quality of life of patients with anorexia nervosa (AN) was com-pared to published norms for the general Chinese people. Methods 49 AN outpatients or inpatients were evalua-ted by the Self-rated medical outcomes study SF-item Short-Form Health Survey(SF-36). Results The factor scores of role-physical, general health,social function,role emotion, mental health in SF-36 were found significantly lower in AN patient (44.4±36.2,53.3±16.3,56.6±24.1,45.6±38.9,47.5±21.4, respective ) compared with control group(P<0.01 ). The factor scores of physical function,bodily pain, general health in SF-36 were found significantly lower in AN patient with long period (85.5±13.4,74.0±20.3,45.8±14.7, respective) compared with AN patient with short period (93.2±6.6,87.2±14.7,57.5±15.7, respective) (P<0.05). Con-clusions AN is associated with impaired health-related quality of life.