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Para-aortic lymph node evaluation in cervical cancer: the impact of staging upon treatment decisions and outcome
Authors:Petereit  Hartenbach  & Thomas
Institution:Department of Radiation Oncology, University of Wisconsin Medical School, Madison Wisconsin USA; Department of Obstetrics and Gynecology, University of Wisconsin Medical School, Madison Wisconsin USA; University of Toronto, Toronto-Sunnybrook, Regional Cancer Center, Toronto, Canada
Abstract:Petereit DG, Hartenbach EM, Thomas GM. Para-aortic lymph node evaluation in cervical cancer: the impact of staging upon treatment decisions and outcome. Int J Gynecol Cancer 1998; 8 :353–364.
This article reviews both surgical and nonsurgical staging options for cervical cancer and determines the ultimate impact of these staging pathways. Surgical staging is the most sensitive method for detecting para-aortic lymph node metastases; however, a negative lymphangiogram precludes surgical staging since it is a highly sensitive and specific radiographic study. CT and MRI are not as sensitive for detecting para-aortic disease, therefore a false negative study would ultimately result in the loss of about 4 stage IIB and 5 stage IIIB patients out of 100. Judicious use of existing staging options will enhance the ultimate benefit to individual patients, rather than surgically staging all patients prior to radiotherapy.
Keywords:cervical cancer  para-aortic lymph nodes  radiation  surgical staging
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