| 采用木菠萝凝集素检测胃液中胃蛋白酶的临床研究 |
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| 引用本文： | 罗志,谢翠英,周素芳.采用木菠萝凝集素检测胃液中胃蛋白酶的临床研究[J].华夏医学,1999(2). |
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| 作者姓名： | 罗志 谢翠英 周素芳 |
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| 作者单位： | 广西柳州卫校生理教研室(罗志)，柳州铁路中心医院(谢翠英)，广西医科大学生化教研室(周素芳) |
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| 摘 要： | 目的：探讨胃蛋白酶在胃部疾病中的作用。方法：采用ＨＲＰ标记ｊａｃａｌｉｎ，通过ＥＬＩＳＡ法检测各种胃病患者胃液中的胃蛋白酶。结果：胃蛋白酶在正常组（１５例）、胃炎组（３０例）、十二指肠溃疡组（３０例）、胃溃疡组（３０例）及胃癌组（１０例）中含量无显著性差异，但胃液ｐＨ＜３的胃蛋白酶含量明显高于ｐＨ＞４的酶含量，表明胃酸增加，胃蛋白酶的分泌亦增加，但胃蛋白酶与胃部疾病的发生关系不密切。结论：胃粘膜屏障的局部缺陷使之对胃蛋白酶抵抗力下降，可能与消化性溃疡的发生关系更为密切。
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| 关 键 词： | 木菠萝凝集素 酶联免疫测定 胃液 胃蛋白酶 |
Clinic Study of the Gastric Juice Pepsin Assay by Enzymelabeled Jacalin |
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| Luo ZhiLiuzhou Health School.Guangxi.Clinic Study of the Gastric Juice Pepsin Assay by Enzymelabeled Jacalin[J].Acta Medicinae Sinica,1999(2). |
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| Authors: | Luo ZhiLiuzhou Health SchoolGuangxi |
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| Institution: | Liuzhou545005 |
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| Abstract: | Objective: To study the effects of Gastrie Juice pepsin on gastric disease. Methods: The pepsin contents of gastric juice were determined by JacalinHRP ELISA assay.Result:There were no significant differences in the pepsin contents among the normal controls and patients with various gastric diseases including gastritis,duodenal ulcer,peptic ulcer and carcinoma of stomach.But the pepsin contents of the gastric secretions with pH<3 were significantly higher than those with pH>4.Conclusion: The resistance to the gastric juice pepsin is decreased by the local defect of the gastric mucus barrier.it may be correlative with gastric ulcer. |
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| Keywords: | jacalin ELISA gastric juice pepsin |
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