| 白念珠菌基因微卫星多态性与分型探讨 |
| |
| 引用本文： | 张军民,王汉平,鲁长明,席丽艳,曾凡钦.白念珠菌基因微卫星多态性与分型探讨[J].中国麻风皮肤病杂志,2002,18(1):1-2. |
| |
| 作者姓名： | 张军民 王汉平 鲁长明 席丽艳 曾凡钦 |
| |
| 作者单位： | 1. 中山医科大学孙逸仙纪念医院皮肤科,广州,510120
2. 广州第一人民医院血液内科,510180 |
| |
| 摘 要： | 目的 : 研究白念珠菌的基因微卫星多态性特征 ,探讨新的白念珠菌的分型方法。方法 : 应用聚合酶链反应技术对 31株白念珠菌的启动子序列延伸因子 3基因的微卫星多态性作了分析。结果 : 检测到 9个等位基因 ,10种不同白念珠菌基因型 ,其基因型特征在继代培养后仍保持稳定。结论 : 该方法快捷、重复性好 ,可用于白念珠菌的流行病学调查和可能的基因学诊断中
|
| 关 键 词： | 白念珠菌 微卫星多态性 |
| 修稿时间： | 2001年1月31日 |
Microsatellite Polymophism of Candida albicans gene and its typing |
| |
| Zhang Junmin,Wang Hanping,Lu Changming,et al..Microsatellite Polymophism of Candida albicans gene and its typing[J].China Journal of Leprosy and Skin Diseases,2002,18(1):1-2. |
| |
| Authors: | Zhang Junmin Wang Hanping Lu Changming |
| |
| Institution: | Zhang Junmin,Wang Hanping,Lu Changming,et al. Department of Dermatology,Sun Yat-sen Memorial Hospital,Sun Yat-sen Medical University,Guangzhou,510120 |
| |
| Abstract: | Objective: To investigate the microsatellite polymorphism of candia albicans and to create a new typing system.Methods: The polymorphism of a TTC/TTTC microsatellite in the promoter sequence of the elongation factor-3 genes in 31 strains of candida albicans was studied by polymerase chain reaction. Results:Nine alleles and 10 profiles of genes were found. This marker was stable even after successive cultures. Conclusion: As a rapid and reproducible method, the marker can be used for the study of epidemiology and genetic characterization of candida albicans. |
| |
| Keywords: | microsatellite polymorphism candida albicans |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
