用颈椎骨龄对单侧完全性唇腭裂患者发育情况的评估

目的：用颈椎骨龄来评估单侧完全性唇腭裂（unilateral complete cleft lip and palate ，UCLP）患者的发育情况。方法将45例9～16岁的UCLP患者作为试验组（UCLP组）；另选取年龄、种族与UCLP组相匹配的45例非唇腭裂（none cleft lip and palate，Non?cleft）患者作为对照组（Non?cleft组）。拍摄头颅定位侧位片。通过头颅定位侧位片分别测量计算UCLP组与Non?cleft组的颈椎骨龄。对相同性别的UCLP组与Non?cleft组分别进行独立样本t检验。结果 UCLP组男性患者的颈椎骨龄比Non?cleft组小且差异有统计学意义（P<0.05），而UCLP组女性患者的颈椎骨龄与Non?cleft组差异无统计学意义（P>0.05）。结论与Non?cleft患者相比，9～16岁年龄段男性UCLP患者的发育相对迟缓，而女性患者之间无明显差异。

Use cervical vertebra bone age to evaluate the development situation of unilateral complete cleft lip and palate patients

Objective Use cervical vertebra bone age to assess the development situation of the patients with unilat?eral complete cleft lip and palate (UCLP). Methods A total of 45 UCLP patients aged 9 to 16 years were selected as ex?perimental group. Another 45 patients of the same age and race without cleft lip and palate were selected as control group. Lateral cephalometric radiographs were taken for the patients. Lateral cephalometric radiographs were used to measure and calculate vertebra bone of the UCLP group and the Non?cleft group. Independent samples t test was used to compare bone age of UCLP group and the Non?cleft group in same gender. Results Cervical vertebra bone age of male patients in UCLP group was significantly smaller than patients in the Non?cleft group (P<0.05), while cervical vertebra bone age of female patients shows no significant difference between two groups (P>0.05). Conclusion Compared with Non?cleft pa?tients, the male UCLP patients ’ development is relatively slow. And there is no significant difference between the female patients in two groups.