超促排卵周期胚胎移植日血清孕酮/雌二醇比值对胚胎着床的影响

目的：探讨超促排印周期胚胎移植日血清孕酮／雌二醇（P／E2）比值对子宫内膜容受性的影响。方法：将96例体外受精-胚胎移植患者按胚胎移植日（ET）血清P／E2比值分为5组，对其实验室结果和临床结局进行比较。结果：5组患者的平均年龄、ET日内膜厚度、受精率、印裂率、可移植胚胎数及移植胚胎数均无差异（P〉0．05）。组1的取卵数最多，妊娠率低；组5的取卵数最少，无1例妊娠。而组3（P／E2为100～150）获得显著高于其他组的妊娠率和单胚种植率（P〈0．05）。结论：恰当的P／E2比值可提高子宫内膜的容受性，在促排卵周期测定ET日的P／E2比值对预测妊娠成功与否有参考作用。

The clinical study of relationship between serum P/E2 ratio on the day of embryo transfer and embryo implantation

Objective: To study the effect of serum P/E2 ratio on the day of embryo transfer in controlled ovarian hyperstimulation(COH) on implantation.Methods: 96 cases of IVF were divided into five groups according to serum P/E2 ratio on embryo transfer(ET) day,and their laboratory results and clinical outcomes were compared.Results: There were no differences on average age,endometrium thickness on ET day,fertilization rates,embryo cleavage rates,and numbers of embryos transferred among five groups(P>0.05).There was the most and the least oocytes in group 1(P/E2<50) and group 5(P/E2>200),respectively.No patient in group 5 became pregnant finally,while those in group 3(P/E2100~150) got higher pregnancy rates and single embryo implantation rates than other four groups(P<0.05).Conclusion: The optimal P/E2 ratio on the day of ET can improve endometrial receptivity.It is important to monitor serum P/E2 on the day ET to predict pregnancy in COH.