| 八仙花叶化学成分研究 |
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| 引用本文： | 王知斌,郭江涛,杨春娟,孟永海,王秋红,杨炳友,匡海学. 八仙花叶化学成分研究[J]. 中国中药杂志, 2013, 38(5): 709-713 |
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| 作者姓名： | 王知斌 郭江涛 杨春娟 孟永海 王秋红 杨炳友 匡海学 |
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| 作者单位： | 1. 黑龙江中医药大学北药基础与应用研究教育部重点实验室,黑龙江省中药及天然药物药效物质基础研究重点实验室,黑龙江哈尔滨150040
2. 哈尔滨医科大学药学院,黑龙江哈尔滨,150081 |
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| 基金项目： | 黑龙江省教育厅科学技术研究项目(12511512);黑龙江省博士后项目(LBH-Z10021) |
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| 摘 要： | 目的:对中草药八仙花叶的化学成分进行研究.方法:采用硅胶柱色谱、ODS柱色谱和HPLC等手段进行分离纯化,并通过1H,13C-NMR,MS等波谱方法鉴定结构.结果:分离鉴定了11个化合物,包括三萜类3个,分别为泽屋萜(1),白桦脂醇(2),白桦脂酸(3)；含氮类化合物6个,分别为2-乙基-3-甲基-马来酰亚胺-N-β-D-葡萄糖苷(4),尿嘧啶核苷(5),胸腺核苷(6),阿糖腺苷(7),烟酰胺(8),焦谷氨酸甲酯(9)；异香豆素类2个,分别为绣球酚(10),绣球酚-4’-O-β-D-葡萄糖苷(11).结论:化合物1～4和7～9为首次从该属植物中分离得到.
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| 关 键 词： | 虎耳草科 八仙花 三萜 含氮类化合物 异香豆素 |
| 收稿时间： | 2012-10-19 |
Chemical constituents from Hydrangea macrophylla |
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| WANG Zhi-bin,GUO Jiang-tao,YANG Chun-juan,MENG Yong-hai,WANG Qiu-hong,YANG Bing-you and KUANG Hai-xue. Chemical constituents from Hydrangea macrophylla[J]. China Journal of Chinese Materia Medica, 2013, 38(5): 709-713 |
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| Authors: | WANG Zhi-bin GUO Jiang-tao YANG Chun-juan MENG Yong-hai WANG Qiu-hong YANG Bing-you KUANG Hai-xue |
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| Affiliation: | Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Heilongjiang Key Laboratory of Traditional Chinese Medicine Pharmacodynamic Material Bases, Harbin 150040, China;Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Heilongjiang Key Laboratory of Traditional Chinese Medicine Pharmacodynamic Material Bases, Harbin 150040, China;School of Pharmacy, Harbin Medical University, Harbin 150081, China;Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Heilongjiang Key Laboratory of Traditional Chinese Medicine Pharmacodynamic Material Bases, Harbin 150040, China;Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Heilongjiang Key Laboratory of Traditional Chinese Medicine Pharmacodynamic Material Bases, Harbin 150040, China;Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Heilongjiang Key Laboratory of Traditional Chinese Medicine Pharmacodynamic Material Bases, Harbin 150040, China;Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Heilongjiang Key Laboratory of Traditional Chinese Medicine Pharmacodynamic Material Bases, Harbin 150040, China |
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| Abstract: | |
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| Keywords: | Saxifragaceae Hydrangea macrophylla triterpenoid nitrogenous compounds isocoumarin |
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