| 现代生物技术在人参属药用植物研究中的应用 |
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| 引用本文： | 陈士林,朱孝轩,陈晓辰,牛云云,张鑫,宋经元,罗红梅,孙超.现代生物技术在人参属药用植物研究中的应用[J].中国中药杂志,2013,38(5):633-639. |
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| 作者姓名： | 陈士林 朱孝轩 陈晓辰 牛云云 张鑫 宋经元 罗红梅 孙超 |
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| 作者单位： | 1. 中国医学科学院北京协和医学院药用植物研究所濒危药材繁育国家工程实验室,北京100193 ;中国中医科学院中药研究所,北京100700
2. 中国医学科学院北京协和医学院药用植物研究所濒危药材繁育国家工程实验室,北京,100193 |
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| 基金项目： | 国家科技支撑计划项目(2011BAI03B01);吉林省重大科技计划项目;教育部长江学者和创新团队发展计划项目(IRT1150) |
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| 摘 要： | 该文对DNA条形码等分子鉴定技术、一代和二代测序技术、基因克降等现代牛物技术在人参属药用植物的物种鉴定、转录组分析、次生代谢产物合成途径及关键酶功能鉴定研究中的应用进行综述.现代牛物技术为人参属药用植物在分子水平的研究提供保证,揭示了人参属药用植物转录组及功能基因等遗传信息,加速了人参属药用植物基因组图谱绘制,为阐明人参属植物中重要次生代谢产物——人参皂苷合成的分子机制、实现体外合成重要天然产物以及对未来新药物的研发奠定基础.
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| 关 键 词： | 人参属药用植物 DNA条形码 转录组 人参皂苷 次生代谢合成途径 功能基因 |
| 收稿时间： | 2013/2/18 0:00:00 |
New technologies used for Panax genus research |
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| CHEN Shi-lin,ZHU Xiao-xuan,CHEN Xiao-chen,NIU Yun-yun,ZHANG Xin,SONG Jing-yuan,LUO Hong-mei and SUN Chao.New technologies used for Panax genus research[J].China Journal of Chinese Materia Medica,2013,38(5):633-639. |
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| Authors: | CHEN Shi-lin ZHU Xiao-xuan CHEN Xiao-chen NIU Yun-yun ZHANG Xin SONG Jing-yuan LUO Hong-mei and SUN Chao |
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| Institution: | National Engineering Laboratory for Breeding of Endangered Medicinal Materials, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical, Beijing 100193, China;Institute of Chinese Materia Medica, Academy of Chinese Medical Sciences, Beijing 100700, China;National Engineering Laboratory for Breeding of Endangered Medicinal Materials, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical, Beijing 100193, China;National Engineering Laboratory for Breeding of Endangered Medicinal Materials, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical, Beijing 100193, China;National Engineering Laboratory for Breeding of Endangered Medicinal Materials, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical, Beijing 100193, China;National Engineering Laboratory for Breeding of Endangered Medicinal Materials, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical, Beijing 100193, China;National Engineering Laboratory for Breeding of Endangered Medicinal Materials, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical, Beijing 100193, China;National Engineering Laboratory for Breeding of Endangered Medicinal Materials, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical, Beijing 100193, China;National Engineering Laboratory for Breeding of Endangered Medicinal Materials, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical, Beijing 100193, China |
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