| 乙型肝炎病毒感染者PreS1-Ag、PreS2-Ag与HBV测定分析 |
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| 引用本文： | 金明林,黎明新.乙型肝炎病毒感染者PreS1-Ag、PreS2-Ag与HBV测定分析[J].中国医药导报,2008,5(31):77-78. |
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| 作者姓名： | 金明林 黎明新 |
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| 作者单位： | 1. 沈阳医学院生物化学教研室,辽宁沈阳,110034
2. 沈阳医学院奉天医院检验科,辽宁沈阳,110024 |
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| 摘 要： | 目的：研究乙型肝炎病毒（HBV）感染者PreS1-Ag和PreS2-Ag与HBV-M之间的关系。方法：用ELISA法对316例HBV感染者血清进行PreS1-Ag和PreS2-Ag及HBV-M检测。结果：对照组的血清PreS1-Ag和PreS2-Ag与HBV-M为阴性，而HBV感染者血清PreS1-Ag和PreS2-Ag在三种主要模式中的检出率分别为88．8％，76．3％；70．3％，55．4％；68．2％，55．7％。结论：PreS1-Ag和PreS2-Ag更敏感地反映了HBV的感染和复制程度，对乙肝血清标志物检测起重要的补充作用。
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| 关 键 词： | 乙型肝炎病毒 PreS1-A PreS2-Ag |
The PreS1-Ag,PreS2-Ag and HBV determination and analysis of hepatitis B virus infected person |
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| JIN Ming-Lin,LI Ming-Xin.The PreS1-Ag,PreS2-Ag and HBV determination and analysis of hepatitis B virus infected person[J].China Medical Herald,2008,5(31):77-78. |
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| Authors: | JIN Ming-Lin LI Ming-Xin |
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| Institution: | JIN Ming-Lin, LI Ming-Xin(1.Department of Biochemistry, Shenyang Medical College, Shenyang 110034; 2.Clinical Laboratory, Shenyang Medical College Fengtian Hospital, Shenyang 110024, China) |
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| Abstract: | Objective: To study the correlation of PreS1-Ag,PreS2-Ag and HBV-M in hepatitis B virus (HBV) infected person. Methods: ELISA method was used in the detection PreS1-Ag,PreS2-Ag and HBV-M in serum of 316 cases of HBV-infected people. Results: The control group serum PreS1-Ag,PreS2-Ag and HBV-M was negative, but HBV infect- ed group PreS1-Ag,PreS2-Ag and HBV-M detection rates in three models were 88.8%,76.3%; 70.3%,55.4%; 68.2%, 55.7%. Conclusion: PreS1-Ag and PreS2-Ag were more sensitive to HBV infection and replication level and play an im- portant supplementary role in HBV serum markers detection. |
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| Keywords: | PreS1-A PreS2-Ag |
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