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布洛芬缓释胶囊中布洛芬含量的测量不确定度评估
引用本文:屈颖.布洛芬缓释胶囊中布洛芬含量的测量不确定度评估[J].天津药学,2008,20(1):8-10.
作者姓名:屈颖
作者单位:天津市药品检验所,天津,300070
摘    要:目的:对高效液相色谱法(HPLC)测定布洛芬缓释胶囊中布洛芬含量的测量不确定度进行评估.方法:采用HPLC法测定布洛芬的含量,建立数学模型,分析不确定度来源.结果:通过对各变量的分析,计算各变量的不确定度,最后计算出合成标准不确定度.结论:本方法建立的数学模型合理、可靠.

关 键 词:高效液相色谱法  布洛芬缓释胶囊  测量不确定度  布洛芬  缓释胶囊  含量  测量不确定度  不确定度评估  Capsule  Sustained  Release  Ibuprofen  determination  uncertainty  合成标准不确定度  计算  变量  结果  不确定度来源  分析  数学模型  方法  测定  HPLC
文章编号:1006-5687(2008)01-0008-03
收稿时间:2007-07-08
修稿时间:2007年7月8日

Evaluating of measurement uncertainty for determination of ibuprofen in Ibuprofen Sustained Release Capsule
Qu Ying.Evaluating of measurement uncertainty for determination of ibuprofen in Ibuprofen Sustained Release Capsule[J].Tianjin Pharmacy,2008,20(1):8-10.
Authors:Qu Ying
Abstract:OBJECTIVE To evaluate the uncertainty of measurement for determination of ibuprofen in Ibuprofen Sustained Release Capsule by HPLC. METHODSS The content of Ibuprofen in Ibuprofen Sustained Release Capsule determined by HPLC. Specify the statistical approach, identify the components of uncertainty. RESULTS Every components of uncertainty was evaluated by analyzing the various variable parameters among the procedures. The combined uncertainty was then finally obtained by synthesizing the uncertainties of various component variables. CONCLUSION The Statistical approach of measurement uncertainty established in this paper is reasonable and reliable.
Keywords:HPLC  Ibuprofen Sustained Release Capsule  measurement uncertainty
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