| 血脉舒颗粒剂对小鼠抗炎镇痛作用的实验研究 |
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| 引用本文： | 郝伟,隋璐.血脉舒颗粒剂对小鼠抗炎镇痛作用的实验研究[J].中国医药导报,2011,8(20):29-30. |
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| 作者姓名： | 郝伟 隋璐 |
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| 作者单位： | 1. 沈阳医学院机能实验中心,辽宁沈阳,110034
2. 沈阳医学院病理生理教研室,辽宁沈阳,110034 |
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| 摘 要： | 目的：观察血脉舒颗粒剂对小鼠的抗炎及镇痛作用。方法：将昆明种小鼠随机分为5组,分别为空白对照组,血脉舒颗粒剂高、中、低剂量组和阿司匹林组。给小鼠灌胃（ig）给药5 d后,采用二甲苯致小鼠急性耳肿胀试验观察血脉舒颗粒剂的抗炎作用;采用醋酸扭体法和热板镇痛法观察血脉舒颗粒剂对小鼠的镇痛作用。结果：血脉舒颗粒剂中、高剂量组对于二甲苯所致的小鼠急性耳肿胀和有显著的抑制作用,对小鼠醋酸所致的扭体及热板法致痛反应有较好的止痛作用,镇痛疗效呈剂量依赖关系。结论：血脉舒颗粒剂具有显著的抗炎、止痛疗效。
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| 关 键 词： | 血脉舒颗粒剂 抗炎作用 镇痛作用 |
Experimental study of inflammatory and analgesic effect of Xuemaishu Granules in mice |
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| HAO Wei,SHUI Lu.Experimental study of inflammatory and analgesic effect of Xuemaishu Granules in mice[J].China Medical Herald,2011,8(20):29-30. |
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| Authors: | HAO Wei SHUI Lu |
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| Institution: | HAO Wei1,SHUI Lu2 1.Function Experiment Center,Shenyang Medical College,Liaoning Province,Shenyang 110034,China,2.Pathophysiology Department |
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| Abstract: | Objective:To observe the anti-inflammatory and analgesic effect of Xuemaishu Granules in mice.Methods:Kunming mices were randomly divided into 5 groups as black control group,Xuemaishu Granules at high,medium and low doses groups while Aspirin was used in the control group.The anti-inflammatory effect of Xuemaishu Granules was administered(ig) for 5 days to mices.Acute ear swelling test was used which was caused by Xylene in mice to observe the inflammatory effect of Xuemaishu Granules;acetic acid-writhing ... |
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| Keywords: | Xuemaishu Granules Anti-inflammatory effect Analgesic effect |
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