局部放疗联合唑来膦酸治疗骨转移癌痛

目的探讨局部放疗联合唑来膦酸对骨转移癌患者的镇痛效果。方法 32例骨转移癌患者,局部放疗,DT总量3000 cGy/10f/2W,给予唑来膦酸4mg加入生理盐水100ml中,静脉滴注时间不<15min,d1,每4周为1周期;用药2周期后评价疗效。结果 32例患者中,疼痛完全缓解(CR)23例,部分缓解(PR)5例,无缓解(NR)4例,总有效率87.5%(28/32);毒副反应主要是发热、肌肉疼痛、恶心、呕吐等,经对症处理后恢复。结论局部放疗联合唑来膦酸对骨转移癌患者镇痛效果较好,且毒副反应可耐受。

Local radiotherapy combined Zoledronic acid treatment of bone metastases a cancer pain

Objective To explore the analgesic effect of local radiotherapy combined Zoledronic acid treatment of metastatic bone tumors.Methods 32 patients with a history of bone metastases,were treated with a regimen including local radiotherapy,3000 cGy/10f/2W,and intravenous Zoledronic acid at 4 mg in 100 ml 0.9% sodium chloride over 15 min,every 4 weeks for one cycle.All patients were assessed every 2 cycles.Results The results showed,23 patients achieved complete pain relief(CR),5 patients had partial catabatic(P...