| 小儿咳嗽变异性哮喘与肺炎支原体感染相关性研究 |
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| 引用本文： | 伍亚辉,杨晓鸥,刘翠梅,盛珺,戈志峰,周韵娇,管益芳.小儿咳嗽变异性哮喘与肺炎支原体感染相关性研究[J].中国医药导报,2011,8(21):54-56. |
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| 作者姓名： | 伍亚辉 杨晓鸥 刘翠梅 盛珺 戈志峰 周韵娇 管益芳 |
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| 作者单位： | 上海市闵行吴泾医院,上海,200241 |
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| 基金项目： | 上海市闵行区自然科学研究课题 |
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| 摘 要： | 目的：探讨小儿咳嗽变异性哮喘与肺炎支原体感染发病的关系。方法：收集小儿咳嗽变异性哮喘患儿55例、支气管哮喘患儿53例、肺炎支原体感染患儿（包括肺炎及支气管炎）55例及对照组患儿43例,采用颗粒凝集法检测小儿咳嗽变异性哮喘患儿及对照组患儿血清肺炎支原体IgM抗体（MP-IgM）;同时采用ELISA方法和抗凝静脉血、伊红染色、光学显微镜检测小儿咳嗽变异性哮喘患儿、支气管哮喘患儿、肺炎支原体感染患儿和对照组患儿血清总IgE水平和计数嗜酸粒细胞。结果：小儿咳嗽变异性哮喘患儿MP-IgM阳性率为43.6%,显著高于对照组患儿MP-IgM阳性率（18.6%）（P〈0.05）;小儿咳嗽变异性哮喘患儿、支气管哮喘患儿、肺炎支原体感染患儿外周血计数嗜酸粒细胞及血清总IgE水平明显高于对照组患儿（H=16.236、H=65.379,均P〈0.05）,且支气管哮喘患儿血嗜酸粒细胞计数及血清总IgE大于小儿咳嗽变异性哮喘患儿（median=0.50、0.44;median=180.5、170.2）,小儿咳嗽变异性哮喘患儿血嗜酸性粒细胞计数及血清总IgE大于肺炎支原体感染患儿（median=0.44、0.32;median=170.2、159.10）。结论：小儿咳嗽变异性哮喘与肺炎支原体感染发病密切相关。
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| 关 键 词： | 咳嗽变异性哮喘 小儿 肺炎支原体感染 |
Research of correlation between cough variant asthma in children and mycoplasma pnenumonia infection |
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| WU Yahui,Yang Xiaoou,LIU Cuimei,SHENG Jun,GE Zhifeng,ZHOU Yunjiao,GUAN Yifang.Research of correlation between cough variant asthma in children and mycoplasma pnenumonia infection[J].China Medical Herald,2011,8(21):54-56. |
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| Authors: | WU Yahui Yang Xiaoou LIU Cuimei SHENG Jun GE Zhifeng ZHOU Yunjiao GUAN Yifang |
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| Institution: | WU Yahui,Yang Xiaoou,LIU Cuimei,SHENG Jun,GE Zhifeng,ZHOU Yunjiao,GUAN Yifang Wujing Hospital of Minhang District in Shanghai City,Shanghai 200241,China |
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| Abstract: | Objective: To determine the relationship between cough vaviant asthma(CVA) in children and mycoplasma pnenumonia(MP) infection.Methods: 55 cases of CVA in children,53 cases of bronchial asthma in children,55 cases of MP infection(including pneumonia and bronchitis) in children,43 cases of control group.The MP-IgM antibody level was determined by particle agglutination method in CVA children and the control group.Meantime total serum IgE level and the count of Eosinophics(EOS) determined by ELISA methods and... |
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| Keywords: | Cough variant asthma Children Mycoplasma pnenumonia infection |
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