| 神经节苷脂治疗早产儿颅内出血致脑损伤的临床研究 |
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| 引用本文： | 赖龙龙,张旭东. 神经节苷脂治疗早产儿颅内出血致脑损伤的临床研究[J]. 中国医药导报, 2011, 8(19): 70-71 |
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| 作者姓名： | 赖龙龙 张旭东 |
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| 作者单位： | 广东省汕尾逸挥基金医院,广东汕尾,516600 |
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| 摘 要： | 目的：观察神经节苷脂辅助治疗早产儿颅内出血所致的脑损伤的临床效果。方法：将98例颅内出血致脑损伤患儿随机分为治疗组和对照组,每组49例。对照组采用综合治疗,治疗组在综合治疗的同时加入神经节苷脂进行干预治疗,观察并比较两组的临床疗效及其行为神经评分（NBNA评分）。结果：治疗组49例患儿中,38例（77.55%）显效,总有效率为95.92%;对照组24例（48.98%）显效,总有效率为77.55%。两组显效率和总有效率比较,差异均有统计学意义（P〈0.05）;20项NBNA测定结果显示,两组患儿在治疗1个疗程以后,NBNA评分均有改善,但治疗组改善显著优于对照组（P〈0.05）。结论：神经节苷脂治疗早产儿颅内出血致脑损伤有较好的临床疗效,可以显著降低患儿的病死率和神经系统后遗症的发生率。
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| 关 键 词： | 颅内出血 新生儿 神经节苷脂 神经系统后遗症 |
The clinical research of ganglioside to preterm children with brain damage caused by intracranial hemorrhage |
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| LAI Longlong,ZHANG Xudong. The clinical research of ganglioside to preterm children with brain damage caused by intracranial hemorrhage[J]. China Medical Herald, 2011, 8(19): 70-71 |
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| Authors: | LAI Longlong ZHANG Xudong |
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| Affiliation: | LAI Longlong,ZHANG Xudong Shanwei Yihui Foundation Hospital,Guangdong Province,Shanwei 516600,China |
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| Abstract: | Objective:To observe the clinical effect of ganglioside to preterm children with brain damage induced by intracranial hemorrhage.Methods:98 cases with intracranial hemorrhage induced brain injury were randomly divided into treatment group and control group,with 49 patients in each group.The control group was treated with integrated therapy,while the treatment group added ganglioside based on the integrated treatment,the clinical efficacy and NBNA score of the two groups were observed and compared.Results:Am... |
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| Keywords: | Intracranial hemorrhage Newborn Ganglioside Neurological sequelae |
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