| 心血管疾病基因治疗的分子影像学研究进展 |
| |
| 引用本文： | 张淼 综述,李彪 审校.心血管疾病基因治疗的分子影像学研究进展[J].中国医学影像技术,2009,25(8):1512-1514. |
| |
| 作者姓名： | 张淼 综述 李彪 审校 |
| |
| 作者单位： | 上海交通大学医学院附属瑞金医院核医学科,上海,200025 |
| |
| 基金项目： | 上海市教委重点学科建设基金 |
| |
| 摘 要： | 近年来,利用基因治疗心血管疾病的实验与临床前期研究取得了较快的发展.分子影像学是在分子或细胞水平上研究活体生命或疾病过程的特定分子事件的新技术,为心血管疾病的基因治疗提供了一种实时、无创地检测方法,促进了这一治疗模式的发展和完善.本文主要综述分子影像学在心血管疾病基因治疗中的应用,包括分子探针、成像技术(包括核医学、MRI、超声、光学成像)的进展.
|
| 关 键 词： | 分子影像学 心血管疾病 报告基因 |
| 收稿时间： | 2008/10/14 0:00:00 |
| 修稿时间： | 2009/3/22 0:00:00 |
Advances of molecular imaging in gene therapy of cardiovascular diseases |
| |
| ZHANG Miao and LI Biao.Advances of molecular imaging in gene therapy of cardiovascular diseases[J].Chinese Journal of Medical Imaging Technology,2009,25(8):1512-1514. |
| |
| Authors: | ZHANG Miao and LI Biao |
| |
| Institution: | Department of Nuclear Medicine, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China;Department of Nuclear Medicine, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China |
| |
| Abstract: | In recent years, experimental and preclinical studies for gene therapy of cardiovascular diseases achieved rapid developments. Molecular imaging is a novel discipline with the goal to display and quantify molecular and cellular targets in vivo, providing a real-time, non-invasive method to monitor gene therapy of cardiovascular diseases and promoting the development and perfection of this therapeutic mode. The application of molecular imaging in gene therapy of cardiovascular diseases including the advances of molecular probes and imaging technologies (nuclear medicine, MRI, ultrasound imaging and fluorescent) were reviewed in this article. |
| |
| Keywords: | Molecular imaging Cardiovascular disease Reporter gene |
| 本文献已被 万方数据 等数据库收录！ |
| 点击此处可从《中国医学影像技术》浏览原始摘要信息 |
| 点击此处可从《中国医学影像技术》下载免费的PDF全文 |
|
