血清CA125、CA199、CEA及VEGF联合检测在卵巢癌诊断中的意义研究

目的：探讨血清CA125、CA199、CEA及VEGF联合检测在卵巢癌诊断中的意义。方法：选取2008年12月～2010年12月于本院进行治疗的32例卵巢癌患者为观察组,选取同期的32例卵巢良性肿瘤患者为对照组,后将两组患者的血清CA125、CA199、CEA及VEGF水平进行统计检测及比较。结果：观察组的血清CA125、CA199、CEA及VEGF阳性率及含量均显著高于对照组,且卵巢癌患者中随分期增加,水平和阳性率呈增高趋势,P〈0.05或P〈0.01,差异有统计学意义。结论：血清CA125、CA199、CEA及VEGF联合检测在卵巢癌诊断中有重要的作用,可提高检出率及了解病情严重程度。

The study on the significance of combined detection of serum CA125, CA199,CEA and VEGF in diagnosis of ovarian cancer

Objective：To study the significance of combined detection of serum CA125,CA199,CEA and VEGF in diagnosis of ovarian cancer.Methods：32 patients with ovarian cancer in our hospital from December 2008 to December 2010 were selected as observation group,and 32 patients with benign ovarian tumor at the same time were selected as control group,then the serum CA125,CA199,CEA and VEGF of two groups were detected and compared.Results：The positive rate and content of serum CA125,CA199,CEA and VEGF of observation group were all higher than those of control group,and the positive rate and content levels increased with stage increasing,P0.05 or P0.01,there were significant differences.Conclusion：The combined detection of serum CA125,CA199,CEA and VEGF in diagnosis of ovarian cancer plays an important role,and it can improve the detection rate and investigate disease severity.