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E-cad与ICAM-1在泌尿生殖系统肿瘤中的研究进展
引用本文:徐楗荧,李英勇. E-cad与ICAM-1在泌尿生殖系统肿瘤中的研究进展[J]. 国际医药卫生导报, 2007, 13(19)
作者姓名:徐楗荧  李英勇
作者单位:广东医学院附属医院妇产科,广东湛江,524000
摘    要:细胞粘附分子(cellular adhesion molecules,CAMs)是位于细胞表面的糖蛋白.它通过介导细胞与细胞、细胞与外基质间的相互作用,参与多细胞生物的多种生理及病理过程.E-钙粘附素(E-cad)与细胞间粘附分子-1(ICAM-1)是两种重要的细胞粘附分子,与多种肿瘤的发生发展以及浸润转移关系十分密切,近年来正成为研究的重点和热点.现就 E-cad、ICAM-1在泌尿生殖系统肿瘤中的研究现状特别是与肿瘤的侵袭、浸润与转移关系作一综述.

关 键 词:E-钙粘附素  细胞间粘附分子-1  泌尿生殖系统  肿瘤

Researching Advancement of E-ad and ICAM-1 in Carcinoma of Urogenital System
XU Jianying,LI Yingyong. Researching Advancement of E-ad and ICAM-1 in Carcinoma of Urogenital System[J]. International Medicine & Health Guidance News, 2007, 13(19)
Authors:XU Jianying  LI Yingyong
Abstract:cellular adhesion molecules(CAMs) is a cell-membrance glucoprotein. It participates many physio and patho-processes of organisma multicellularis by con-ducting interaction of cells and cells,cells and ec-substances. Epithelial cadherin(E-cad) and intercellular adhesion molecule-1(ICAM-1) are two important cellular adhesion molecules,impacted on many tumors' development,infiltration,metastasis. They are becoming investigative emphasis and hot spot. Now we reviewing the investigative SQ of E-cad and ICAM-1 in carcinoma of urogenital system,especially associating with invasion and metastasis of carcinoma.
Keywords:Epithelial cadherin Intercellular adhesion molecule-1 Urogenital system Tumor
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