女性腰椎侧位与后前位骨密度的相关性研究

目的分析女性腰椎侧位与后前位骨密度(BMD)的相关性,探索女性腰椎骨密度的变化规律。方法观察166名45~70岁的女性无骨质疏松症状健康体检者,使用GE Lunar Prodigy型双能骨密度仪测量观察对象的腰椎后前位BMD(L2-4BMD)、侧位BMD(B2-4BMD),根据是否绝经及L2-4BMD是否正常,将观察对象分为4组,即未绝经L2-4BMD正常组、未绝经L2-4BMD异常组、绝经后L2-4BMD正常组、绝经后L2-4BMD异常组,分析L2-4BMD、B2-4BMD及其与年龄、体质量指数等的相关关系,并建立回归方程。结果在L2-4BMD正常组,绝经者BMD与未绝经者比较有显著差异,绝经后BMD明显降低;在L2-4BMD异常组,绝经者BMD与未绝经者比较,L2-4BMD明显降低,B2-4BMD无显著差异。各组B2-4BMD与L2-4BMD均具有显著相关关系。绝经后L2-4BMD正常组B2-4BMD与绝经年数的相关有显著统计学意义。多元回归分析显示,因变量B2-4BMD(y)主要由L2-4BMD(X1)、绝经年数(X2)、体质量指数(X3)决定,各组具有相应的回归模型:绝经后L2-4BMD正常组、绝经后L2-4BMD异常组、未绝经L2-4BMD正常组、未绝经L2-4BMD异常组,其B2-4BMD的回归方程分别为:r=0.147+0.501X1-0.007X2,y=-0.437+0.457X1+0.024X3,y=0.102+0.559X1,y=-0.350+0.947X1。结论女性B2-4BMD与L2-4BMD有显著相关关系;女性B2-4BMD与是否绝经、L2-4BMD是否正常有关,绝经后女性更应当早期检查骨密度。

Correlations of lateral position and posyertoanterior lumbar bone mineral density in female

Objective To analyze the dependability of lateral position and P-A position lumbar bone mineral density(BMD) in female and to explore variation regularity of female′s lumbar vertebra BMD.Methods 166(45 yr～70 yr) healthy females were selected,whose P-A position BMD(L2-4BMD) and lateral position BMD(B2-4BMD)were measured by GE Lunar Prodigy dual energy X-ray absorptiometry.Observed objects were divided into 4 groups,pre-menopausal group with normal L2-4BMD,postmenopausal group with abnormal L2-4BMD,post-menopausal group with normal L2-4BMD and post-menopausal group with abnormal L2-4BMD,to analyze the correlations of L2-4BMD,B2-4BMD,years of age and body mass index.Regression equation was then established.Results In the L2-4BMD normal groups,there was significant deviation between pre-menopausal group and post-menopause group and BMD in the post-menopause group decreased rapidly.In the L2-4BMD abnormal groups,significant deviation between pre-menopausal group and post-menopausal group was observed.Compared with L2-4 BMD pre-menopausal group,L2-4BMD in post-menopausal group was significantly decreased while B2-4BMD was not.There were clear-cut correlations between B2-4BMD and L2-4BMD in each group.B2-4BMD in post-menopausal group with normal L2-4 BMD was correlated significantly with years of menopause.Multiple regression analysis showed that dependent variable B2-4BMD(y) was mainly determined by L2-4 BMD(X1),years of menopause(X2) and BMI(X3).Regression equation of each of the 4 groups was: y=0.147+ 0.501 X1-0.007 X2,y=-0.437+0.457 X1+0.024 X3,y=0.102+0.559 X1,y=-0.350+0.947 X1.Conclusion Clear-cut correlations exist between B2-4BMD and L2-4BMD in female.B2-4BMD in female is related to L2-4BMD.Females of post-menopause should check BMD as soon as they can.